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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ClC‑3 / CLCN3 Antibody (aa620‑670, HRP) LS‑C432784
CLCN3 antibody LS-C432784 is an HRP-conjugated rabbit polyclonal antibody to CLCN3 (ClC-3) from human, mouse, rat and other species. Validated for IHC and WB.
Catalog
Size
Price
LS-C432784-100
100 µl (0.65 mg/ml)
$335

Popular ClC-3 / CLCN3 Products

Antibody
Species: Human, Mouse, Rat
Applications: IHC, ICC, Western blot
Antibody
Species: Rat, Human, Mouse
Applications: IHC, ICC, Western blot
CLCN3 antibody LS-C31442 was used in IHC to stain formalin-fixed, paraffin-embedded human brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus, Zebrafish
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Rat, Human, Mouse
Applications: IHC, ICC, Western blot
Antibody
Species: Rat, Human, Mouse
Applications: IHC, ICC, Western blot

Product Description

CLCN3 antibody LS-C432784 is an HRP-conjugated rabbit polyclonal antibody to CLCN3 (ClC-3) from human, mouse, rat and other species. Validated for IHC and WB.

Specifications

Target
Human ClC-3 / CLCN3
Synonyms
CLCN3, Chloride channel protein 3, ClC-3, Chloride channel 3, Chloride transporter ClC-3, CLC3
Host
Rabbit
Reactivity
Human, Chimpanzee, Orangutan, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus, Zebrafish (tested or 100% immunogen sequence identity)
Predicted
Sheep, Drosophila (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Horseradish Peroxidase. Also available Unconjugated or conjugated with FITC, Biotin.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ClC-3 / CLCN3 antibody was raised against synthetic peptide located between aa620-670 of human CLCN3 (P51790, NP_776297). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Platypus, Xenopus, Salmon, Zebrafish (100%); Sheep, Sea squirt, Drosophila (90%); Panda, Lizard (81%).
Epitope
aa620-670
Specificity
Human CLCN3
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
100 mM sodium phosphate, pH 7.6, 150 mM NaCl
Storage
Short term: store at 4°C. Long term: add glycerol to 40-50%, aliquot to avoid freeze-thaw cycles, and store at -20°C. Protect from light.
Restrictions
For research use only.
About ClC-3 / CLCN3
ClC-3 / CLCN3 is a member of the voltage-gated chloride channel (ClC) family. The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles. It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains. The ClC domain catalyzes the selective flow of Cl- ions across cell membranes, and the CBS domain may have a regulatory function. P51790 NM_001829 NP_001820.2


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Images

Immunohistochemistry

CLCN3 antibody LS-C31442 was used in IHC to stain formalin-fixed, paraffin-embedded human brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CLCN3 antibody LS-C31442 was used in IHC to stain formalin-fixed, paraffin-embedded human brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

CLCN3 antibody LS-C31442 was used in IHC to stain formalin-fixed, paraffin-embedded human brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CLCN3 antibody LS-C31442 was used in IHC to stain formalin-fixed, paraffin-embedded human brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

CLCN3 antibody LS-C31442 was used in IHC to stain formalin-fixed, paraffin-embedded human brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CLCN3 antibody LS-C31442 was used in IHC to stain formalin-fixed, paraffin-embedded human brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

CLCN3 antibody LS-C31442 was used in IHC to stain formalin-fixed, paraffin-embedded human brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CLCN3 antibody LS-C31442 was used in IHC to stain formalin-fixed, paraffin-embedded human brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 10/23/2018

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