Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
CD81 antibody was raised against b cell line derived from Burkitt lymphoma
The antibody reacts with the human CD81 (TAPA-1) a 24kD member of the TM4 super family of proteins with four transmembrane domains. The antibody has been shown to have anti-proliferative effects on different lymphoid cell lines particularly those of large cell lymphoma derivation. FUSION PARTNER: NS1 myeloma cells
Flow cytometry. Immunoprecipitation.
PBS, 10 mM Sodium Azide, 1 mg/ml BSA
Short term: store at 4°C. Long term: aliquot and store -20°C. Avoid freeze-thaw cycles. Protect from light. Store undiluted.
CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins.