Menu
Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-C751477-100 100 µg (1 mg/ml) $465 
CD59 Antibody - Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with CD59 Rabbit Recombinant Monoclonal Antibody (MACIF/2867R).
CD59 Antibody - SDS-PAGE Analysis Purified CD59 Rabbit Recombinant Monoclonal Antibody (MACIF/2867R). Confirmation of Purity and Integrity of Antibody.
CD59 Antibody - Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with CD59 Rabbit Recombinant Monoclonal Antibody (MACIF/2867R).
CD59 Antibody - SDS-PAGE Analysis Purified CD59 Rabbit Recombinant Monoclonal Antibody (MACIF/2867R). Confirmation of Purity and Integrity of Antibody.
1 of 2
2 of 2

CD59 Antibody (clone MACIF/2867R, Azide‑free, Carrier‑free) LS‑C751477

CD59 Antibody (clone MACIF/2867R, Azide‑free, Carrier‑free) LS‑C751477

Antibody:
Rabbit Recombinant Monoclonal to Human CD59
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Azide-free, Carrier-free
Other formats:
Price
Catalog Number
$465 
LS-C751477-100
100 µg
1 mg/ml
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Recombinant Monoclonal to Human CD59
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Azide-free, Carrier-free
Other formats:

Specifications

Description
CD59 antibody LS-C751477 is an unconjugated rabbit recombinant monoclonal antibody to human CD59. Validated for IHC.
Target
Human CD59
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Non-Reactivity
Baboon, Horse
Clonality
IgG Recombinant Monoclonal
Clone
MACIF/2867R
Conjugations
Unconjugated
Purification
Purified
Modifications
Azide-free, Carrier-free. Also available Unmodified.
Applications
  • IHC - Paraffin (1 - 2 µg/ml)
  • Applications tested for the base form of this product only
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Recombinant full-length human CD59 protein. Antigen Molecular Weight: 20 kDa
Specificity
Reacts with human CD59, a 20 kDa glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein (Workshop VI; Code N-L036). CD59 regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. CD59 is widely distributed on cells in all tissues. It inhibits formation of MAC, thus protecting cells from complement-mediated lysis. The expression of CD59 on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment, that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobinuria (PNH). This MAb recognizes CD59 transfected cells. It is useful for study on GPI-anchored proteins, PNH and CD59 functions.
Usage
Functional Studies - Flow Cytometry (0.5-1 ug/million cells) - Immunofluorescence (0.5-1 ug/ml) - Optimal dilution for a specific application should be determined.
Presentation
10 mM PBS
Storage
Store at -20°C to -80°C for up to 2 years.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CD59
P13987 NM_000611 NP_000602.1

Publications (0)

Customer Reviews (0)


Requested From: United States
Date Requested: 11/20/2019