Human CD27

Mouse

Human (tested or 100% immunogen sequence identity)

IgG3,k Monoclonal

203.6

Unconjugated

Protein G purified

Azide-free, BSA-free. Also available Unmodified.

Sezary cells were used as the immunogen for the CD27 antibody.

Human CD27

• Immunofluorescence (0.5 - 1 µg/ml)
• Flow Cytometry (0.5 - 1 µg/10E6 cells)

The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27 (Workshop VI. Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis. Optimal dilution of the CD27 antibody should be determined by the researcher.

1X PBS

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P26842 NCBI: NM_001242 NP_001233.1