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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CD121b / IL1R2 Antibody (Internal) LS‑C356122
IL1R2 antibody LS-C356122 is an unconjugated rabbit polyclonal antibody to IL1R2 (CD121b) from human, mouse and rat. Validated for WB.
Catalog
Size
Price
LS-C356122-100
100 µl (1 mg/ml)
$245

Popular CD121b / IL1R2 Products

Antibody
Species: Human
Applications: Flow Cytometry
Anti-IL1R2 antibody IHC of human small intestine, Peyer's patch. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Antibody
Species: Human
Applications: Western blot, Flow Cytometry
Antibody
Species: Human
Applications: ICC, Western blot, Flow Cytometry, ELISA
Western blot. All lanes: Interleukin-1 receptor type 2 antibody at 3 ug/ml+mouse kidney tissue. Secondary antibody: Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 45 kDa. Observed band size: 45 kDa.
Species: Human, Mouse
Applications: Western blot, ELISA

Product Description

IL1R2 antibody LS-C356122 is an unconjugated rabbit polyclonal antibody to IL1R2 (CD121b) from human, mouse and rat. Validated for WB.

Specifications

Target
Human CD121b / IL1R2
Synonyms
IL1R2, CD121b, CD121b antigen, CDw121b, IL-1RT-2, IL1R2c, Interleukin-1 receptor beta, Interleukin-1 receptor type II, IL-1R-beta, Antigen CDw121b, IL-1 type II receptor, IL-1R-2, IL-1RT2, IL1RB, Interleukin-1 receptor type 2
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
Immunogen
CD121b / IL1R2 antibody was raised against kLH-conjugated synthetic peptide encompassing a sequence within the central region of human IL-1R2.
Blocking Peptide
LS-E41635 - Lyophilized - 1 mg - $145.00
Immunizing peptide used to generate LS-C356122. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Internal
Specificity
Recognizes endogenous levels of IL-1R2 protein.
Presentation
PBS, pH 7.3, 0.01% Sodium Azide, 30% Glycerol
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only.
About CD121b / IL1R2
Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. P27930 NM_004633 NP_004624.1


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Images

Western blot

Western blot analysis of IL-1R2 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.
Western blot analysis of IL-1R2 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.

Western blot

Western blot analysis of IL-1R2 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.
Western blot analysis of IL-1R2 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.

Western blot

Western blot analysis of IL-1R2 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.
Western blot analysis of IL-1R2 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.

Western blot

Western blot analysis of IL-1R2 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.
Western blot analysis of IL-1R2 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.

Requested From: United States
Date Requested: 11/16/2018

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