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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCL4 / MIP‑1 Beta Antibody (aa1‑92, HRP) LS‑C706488
MIP-1 Beta antibody LS-C706488 is an HRP-conjugated rabbit polyclonal antibody to MIP-1 Beta (CCL4) from bovine and cow. Validated for WB.
Catalog
Size
Price
LS-C706488-20
20 µl
$215
LS-C706488-100
100 µl
$295
LS-C706488-200
200 µl
$355
LS-C706488-1
1 ml
$740
LS-C706488-10
10 ml
$2,940

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Product Description

MIP-1 Beta antibody LS-C706488 is an HRP-conjugated rabbit polyclonal antibody to MIP-1 Beta (CCL4) from bovine and cow. Validated for WB.

Specifications

Target
Cow CCL4 / MIP-1 Beta
Synonyms
CCL4, ACT2, Act-2, AT744.1, C-C motif chemokine 4, Chemokine (C-C motif) ligand 4, CC chemokine ligand 4, HC21, LAG1, MIP1B, MIP1B1, LAG-1, SCYA2, Secreted protein G-26, SIS-gamma, MIP-1-beta, MIP-1-beta(1-69), Small-inducible cytokine A4, T-cell activation protein 2, G-26, Lymphocyte-activation gene 1, PAT 744, Protein H400, SCYA4
Host
Rabbit
Reactivity
Cow, Bovine (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Horseradish Peroxidase. Also available Unconjugated or conjugated with Biotin, FITC, Cy3, PE, APC, Cy7, APC.
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
Recombinant MIP1b (Met1-Asn92) expressed in E. coli.
Epitope
aa1-92
Specificity
The antibody is a rabbit polyclonal antibody raised against MIP1b. It has been selected for its ability to recognize MIP1b in immunohistochemical staining and western blotting.
Presentation
PBS, pH 7.4, 0.02% Sodium Azide, 50% Glycerol
Storage
Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months.
Restrictions
For research use only.
About CCL4 / MIP-1 Beta
Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. P13236 NM_002984 NP_002975.1


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Images

Western blot

Western blot of recombinant CCL4 / SYCA4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant CCL4 / SYCA4. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of recombinant CCL4 / SYCA4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant CCL4 / SYCA4. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of recombinant CCL4 / SYCA4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant CCL4 / SYCA4. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of recombinant CCL4 / SYCA4.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant CCL4 / SYCA4. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 11/16/2018

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