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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-C12476-100 100 µl $575 
Antibody

Polyclonal Rabbit anti‑Human CASP3 / Caspase 3 Antibody (N‑Terminus, IHC, IF, WB) LS‑C12476

Polyclonal Rabbit anti‑Human CASP3 / Caspase 3 Antibody (N‑Terminus, IHC, IF, WB) LS‑C12476

Antibody:
Rabbit Polyclonal to Human CASP3 / Caspase 3
Application:
IHC, IHC-Fr, ICC, IF, WB, Flo, ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$575 
LS-C12476-100
100 µl
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Human CASP3 / Caspase 3
Application:
IHC, IHC-Fr, ICC, IF, WB, Flo, ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
Caspase 3 antibody LS-C12476 is an unconjugated rabbit polyclonal antibody to Caspase 3 (CASP3) (N-Terminus) from human. It is reactive with human, mouse and rat. Validated for ELISA, Flow, ICC, IF, IHC and WB. Cited in 1 publication.
Target
Human CASP3 / Caspase 3
Synonyms
CASP3 | Apopain | CASP-3 | Caspase-3 | CPP32B | CPP32 | Cysteine protease CPP32 | SCA-1 | SREBP cleavage activity 1 | Yama | Procaspase3 | Caspase 3 | CPP-32 | PARP cleavage protease | Protein Yama
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen (1:200)
  • ICC
  • Immunofluorescence
  • Western blot (1:1000)
  • Flow Cytometry (1:200)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Failed Applications
  • IHC - Paraffin
Immunogen
Synthetic peptide corresponding residues adjacent to Asp175 in N-Terminus of human caspase-3 (KLH coupled).
Epitope
N-Terminus
Specificity
Recognizes cleaved human Caspase 3. Detects endogenous levels of the large fragment (17/19kD) of activated caspase-3 resulting from cleavage adjacent to Asp175. Does not recognize full length caspase-3 or other cleaved caspases. Species cross-reactivity: mouse, bovine, and rat.
Usage
Suitable for use in ELISA, Western Blot, Immunofluorescence, Immunohistochemistry, Immunocytochemistry and Flow Cytometry. Recommend Dilution: Western Blot: 1:1000. Immunohistochemistry (Frozen): 1:200. Immunocytochemistry (IF):1:200. Flow Cytometry: 1:200.
Presentation
10 mM HEPES, pH 7.5, 150 mM NaCl, 0.1 mg/ml BSA, 50% Glycerol, No preservatives added
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CASP3 / Caspase 3
P42574 NM_004346 NP_004337.2

LSBio Ratings

CASP3 / Caspase 3 Antibody (N-Terminus) for IHC, ICC, IF/Immunofluorescence, WB/Western, Flow, ELISA LS-C12476 has an LSBio Rating of
Publications (4)

Publications (1)

Overexpression of facioscapulohumeral muscular dystrophy region gene 1 causes primary defects in myogenic stem cells. Xynos A, Neguembor MV, Caccia R, Licastro D, Nonis A, Di Serio C, Stupka E, Gabellini D. Journal of cell science. May;126:2236-45.

Customer Reviews (0)


Requested From: United States
Date Requested: 7/4/2020