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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CALCRL / CGRP Receptor Antibody (C‑Terminus) LS‑C12352
CGRP Receptor antibody LS-C12352 is an unconjugated rabbit polyclonal antibody to CGRP Receptor (CALCRL) from human and rat. Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C12352-100
100 µl
$725

Popular CALCRL / CGRP Receptor Products

Anti-CALCRL  / CGRP Receptor antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey, Rat, Bovine, Dog, Goat, Hamster, Horse, Pig, Rabbit, Xenopus
Applications: IHC, IHC - Paraffin
Anti-CALCRL  / CGRP Receptor antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human
Applications: IHC, IHC - Paraffin
CALCRL antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Rabbit
Applications: Western blot
Antibody
Species: Rat, Human
Applications: Western blot, ELISA
Western blot analysis of extracts of various cells.
Species: Human, Mouse, Rat
Applications: Western blot

Product Description

CGRP Receptor antibody LS-C12352 is an unconjugated rabbit polyclonal antibody to CGRP Receptor (CALCRL) from human and rat. Validated for ELISA and WB.

Specifications

Target
Rat CALCRL / CGRP Receptor
Synonyms
CALCRL, CGRP type 1 receptor, Cgrp1 receptor, CRLR, Calcitonin receptor-like, CGRP receptor, CGRPR
Host
Rabbit
Reactivity
Rat, Human (tested or 100% immunogen sequence identity)
Predicted
Mouse (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • Western blot (1:1000 - 1:5000)
  • ELISA (1:10000 - 1:50000)
Immunogen
Synthetic peptide consisting of 20aa mapping near the cytoplasmic, C-terminus of rat CRLR (KLH).
Epitope
C-Terminus
Specificity
Recognizes rat Calcitonin Receptor Like Receptor. No significant sequence homology is detected with other CRLR. Species sequence homology: Mouse: 90%; human and chimp: 70%; porcine: 64%.
Usage
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000-1:5000 (ECL). ELISA: 1:10000-1:50000. Control peptide can be used to coat plates at 1 ug/ml.
Presentation
PBS, 40% Glycerol
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About CALCRL / CGRP Receptor
Calcitonin receptor-like receptor (CRLR) is an Adrenomedullin Receptor that requires two additional proteins to function: a chaperone protein RAMP (receptor activity modifying protein) and the component protein RCP. The function of CRLR depends on its interaction with RAMP. When coexpressed with RAMP1, CRLR acts as a receptor for calcitonin gene-related peptide (CGRP). In contrast, when CRLR is coexpressed with either RAMP2 or RAMP3, it acts as a receptor for adrenomedullin. Q16602 NM_005795 NP_005786.1


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Requested From: United States
Date Requested: 11/12/2018

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