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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ATF6 Antibody (aa599‑614) LS‑C357714
ATF6 antibody LS-C357714 is an unconjugated rabbit polyclonal antibody to ATF6 from human, chimpanzee and gibbon. Validated for WB.
Catalog
Size
Price
LS-C357714-100
100 µg (0.5 mg/ml)
$415

Popular ATF6 Products

Anti-ATF6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2564 concentration 10 ug/ml.
Species: Human, Mouse, Rat, Hamster
Applications: IHC, IHC - Paraffin, ICC, Western blot, Chromatin Immunoprecipitation
Anti-ATF6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2516 concentration 5 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, ICC, Western blot
Anti-ATF6 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2430 concentration 5 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, ICC, Western blot, ELISA
Anti-ATF6 antibody IHC of mouse adipose. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5587 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human, Monkey, Rat, Bovine, Guinea pig, Horse, Pig, Rabbit
Applications: IHC, IHC - Paraffin, Western blot
Anti-ATF6 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6032 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA

Product Description

ATF6 antibody LS-C357714 is an unconjugated rabbit polyclonal antibody to ATF6 from human, chimpanzee and gibbon. Validated for WB.
About ATF6
ATF6 is a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. P18850 NM_007348 NP_031374.2

ATF6 Antibody, ATF6-alpha Antibody, ATF6A Antibody


Specifications

Target
Human ATF6
Host
Rabbit
Reactivity
Human, Chimpanzee, Gibbon (tested or 100% immunogen sequence identity)
Predicted
Monkey, Mouse, Rat, Chicken (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.5 - 1 µg/ml)
Immunogen
ATF6 antibody was raised against amino acids 599-614 (NINENVINGQDYEVMM-human). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Baboon, Monkey, Galago, Ferret, Cat, Zebra finch (100%); Marmoset, Mouse, Rat, Chicken (94%).
Epitope
aa599-614
Specificity
Human ATF6
Usage
ATF6 can constitutively induce the promoter of glucose-regulated protein (grp) genes through activation of the endoplasmic reticulum (ER) stress element (ERSE). ATF6 is seen in western blotting between 75~90KD.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
Reconstitution
0.2 ml Sterile distilled water
Storage
Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images

Western blot

Western blot testing of ATF6 antibody and A549 lysate
Western blot testing of ATF6 antibody and A549 lysate

Western blot

Western blot testing of ATF6 antibody and A549 lysate
Western blot testing of ATF6 antibody and A549 lysate

Western blot

Western blot testing of ATF6 antibody and A549 lysate
Western blot testing of ATF6 antibody and A549 lysate

Western blot

Western blot testing of ATF6 antibody and A549 lysate
Western blot testing of ATF6 antibody and A549 lysate

Requested From: United States
Date Requested: 8/18/2018

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