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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ARNT / HIF‑1‑Beta Antibody (aa771‑789) LS‑C3817
Note: This antibody replaces LS-C3818
HIF-1-Beta antibody LS-C3817 is an unconjugated mouse monoclonal antibody to HIF-1-Beta (ARNT) from human, hamster and monkey. Validated for ICC, IP and WB.
Antibody
Catalog
Size
Price
LS-C3817-100
100 µl (1 mg/ml)
$740

Popular ARNT / HIF-1-Beta Products

IHC of human glioblastoma multiforme utilizing anti-HIF-1 Beta.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat, Bovine, Ferret, Sheep, Primate
Applications: IHC, IHC - Paraffin, Western blot
Anti-ARNT antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6007 concentration 5 ug/ml.
Species: Human
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Anti-ARNT antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B492 dilution 1:200.
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Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Immunoprecipitation

Product Description

HIF-1-Beta antibody LS-C3817 is an unconjugated mouse monoclonal antibody to HIF-1-Beta (ARNT) from human, hamster and monkey. Validated for ICC, IP and WB.

Specifications

Target
Human ARNT / HIF-1-Beta
Synonyms
ARNT, ARNT protein, BHLHe2, HIF-1beta, HIF1-beta, HIF1BETA, TANGO, HIF-1-beta, HIF1B
Host
Mouse
Reactivity
Human, Monkey, Hamster (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig (at least 90% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • ICC
  • Western blot
  • Immunoprecipitation
Immunogen
Synthetic peptide corresponding to aa 771-789 (N771SYNNEEFPDLTMFPPFSE789) of human ARNT (Ah receptor nuclear translocator). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Monkey, Marmoset, Hamster (100%); Gibbon, Mouse, Rat, Elephant, Panda, Dog, Bat, Bovine, Horse, Pig, Guinea pig (95%); Rabbit (89%); Opossum (84%).
Epitope
aa771-789
Specificity
Recognizes human, mouse and monkey ARNT. Detects a band of ~87kD by Western blot.
Usage
Immunocytochemistry (1:1000). Immunoprecipitation. Western Blot (1:4000).
Presentation
PBS, 1 mg/ml BSA, 0.05% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About ARNT / HIF-1-Beta
Transcriptional responses to many environmental and developmental stimuli are mediated by the basic helix-loop-helix (bHLH)-PAS family of proteins, which form homodimers that bind regulatory DNA sequences. ARNT/HIF-1 beta regulates the expression of different sets of genes in response to distinct environmental challenges. ARNT forms a complex with arylhydrocarbon receptor (AHR) to activate expression of genes encoding P450. P27540 NM_001668 NP_001659.1


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Requested From: United States
Date Requested: 10/18/2018

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