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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ARNT / HIF‑1‑Beta Antibody (aa496‑789, clone H1beta234) LS‑C2562 Best Seller
HIF-1-Beta antibody LS-C2562 is an unconjugated mouse monoclonal antibody to HIF-1-Beta (ARNT) from human, mouse, rat and other species. Validated for IHC and WB.
Catalog
Size
Price
LS-C2562-100
100 µl (1.4 mg/ml)
$335

Popular ARNT / HIF-1-Beta Products

Anti-ARNT antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6007 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Antibody
Species: Human, Monkey, Hamster
Applications: ICC, Western blot, Immunoprecipitation
Anti-ARNT antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B492 dilution 1:200.
Species: Human, Mouse, Rat, Bovine, Ferret, Sheep
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Immunoprecipitation

Product Description

HIF-1-Beta antibody LS-C2562 is an unconjugated mouse monoclonal antibody to HIF-1-Beta (ARNT) from human, mouse, rat and other species. Validated for IHC and WB.

Specifications

Target
Human ARNT / HIF-1-Beta
Synonyms
ARNT, ARNT protein, BHLHe2, HIF-1beta, HIF1-beta, HIF1BETA, TANGO, HIF-1-beta, HIF1B
Host
Mouse
Reactivity
Human, Mouse, Rat, Bovine, Ferret, Sheep, Primate (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal [H1beta234]
Conjugations
Unconjugated. Also available conjugated with Biotin, DY650, DY488, DY550.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:1000)
  • Western blot (1:500)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Fusion protein containing amino acids 496-789 of human HIF-1 beta
Epitope
aa496-789
Specificity
HIF 1 beta /ARNT.
Presentation
PBS, 0.05% Sodium Azide
Storage
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About ARNT / HIF-1-Beta
Transcriptional responses to many environmental and developmental stimuli are mediated by the basic helix-loop-helix (bHLH)-PAS family of proteins, which form homodimers that bind regulatory DNA sequences. ARNT/HIF-1 beta regulates the expression of different sets of genes in response to distinct environmental challenges. ARNT forms a complex with arylhydrocarbon receptor (AHR) to activate expression of genes encoding P450. P27540 NM_001668 NP_001659.1


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Images

Immunohistochemistry

IHC of human glioblastoma multiforme utilizing anti-HIF-1 Beta.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
IHC of human glioblastoma multiforme utilizing anti-HIF-1 Beta. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

IHC of human glioblastoma multiforme utilizing anti-HIF-1 Beta.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
IHC of human glioblastoma multiforme utilizing anti-HIF-1 Beta. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

IHC of human glioblastoma multiforme utilizing anti-HIF-1 Beta.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
IHC of human glioblastoma multiforme utilizing anti-HIF-1 Beta. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

IHC of human glioblastoma multiforme utilizing anti-HIF-1 Beta.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
IHC of human glioblastoma multiforme utilizing anti-HIF-1 Beta. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 10/16/2018

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