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Anti-ZAK / MLTK Antibody (aa271-300) LS-C101159

Catalog Size Price
LS-C101159-400 400 µl Unavailable

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100% Guaranteed
Rabbit Polyclonal to Human ZAK / MLTK
IHC - Paraffin, Western blot


Human ZAK / MLTK
Human (tested or 100% immunogen sequence identity)
Mouse (at least 90% immunogen sequence identity)
Ammonium sulfate precipitation


  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)

Specificity and Use

LS-E9468 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C101159. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
This MLKLAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-300 amino acids from the Central region of human MLKLAK.


PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About ZAK / MLTK

Q9NYL2 AB049733 NP_057737.2

ZAK Antibody, HCCS-4 Antibody, MLTK Antibody, MLK-related kinase Antibody, MLK7 Antibody, MLT Antibody, MRK Antibody, Mlklak Antibody, AZK Antibody, Mixed lineage kinase 7 Antibody, PK Antibody

ZAK is a MLK(MAP3K) type protein kinase that mediates the cell cycle signals leading to G2 arrest, possibly by regulating cyclin E expression. ZAK is activated in response to osmotic shock with hyperosmolar media through autophosphorylation. The expression of ZAK is increased by activation of the ERK/MAPK pathway and activates the ERK, JNK/SAPK, p38, and ERK5 pathways.


Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot
Western blot of anti-MLKLAK-C284 antibody in HepG2 cell line lysate (35 ug/lane). MLKLAK-C284(arrow) was detected using the purified antibody. This western blot detected isoform 2 of MLKLAK, the accession number for MLKLAK isoform 1 is Q9NYL2, NP_057737.

Requested From: 
Date Requested: 2/25/2018

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