Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
XRCC5, 86 kDa subunit of Ku antigen, CTC85, CTCBF, DNA repair protein XRCC5, G22P2, KARP-1, Ku autoantigen, 80kDa, NFIV, KARP1, Ku86, KUB2, TLAA, Nuclear factor IV, KU80, Thyroid-lupus autoantigen
(tested or 100% immunogen sequence identity)
Ammonium sulfate precipitation
Western blot (0.5 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
XRCC5 / Ku80 antibody was raised against human B cell nuclei from plasmacytoid 2p68 cells.
Recognizes the p80 subunit of Ku at 80kD. The epitope maps to between residues 610-705. Species Reactivity: Human and Monkey. Does not react with bovine, Rabbit, Mouse or Rat.
Suitable for use in ELISA (For coating, Ab can be ordered without BSA), Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blot. Not recommended for. Gel Supershift or Immunohistochemistry. Immunoprecipitation: 2 ug antibody/mg protein lysate. Use Protein G. Western Blot: 0.5 ug/ml.
10 mM PBS, pH 7.4, 15 mM Sodium Azide, 0.2% BSA
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.