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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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XRCC5 / Ku80 Antibody (aa610‑705) LS‑C16171
Ku80 antibody LS-C16171 is an unconjugated mouse monoclonal antibody to Ku80 (XRCC5) from human and monkey. Validated for ELISA, Flow, GS, IF, IHC, IP and WB.
Antibody
Catalog
Size
Price
LS-C16171-500
500 µl
$590

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Product Description

Ku80 antibody LS-C16171 is an unconjugated mouse monoclonal antibody to Ku80 (XRCC5) from human and monkey. Validated for ELISA, Flow, GS, IF, IHC, IP and WB.
About XRCC5 / Ku80
Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. P13010 NM_021141 NP_066964.1

XRCC5 Antibody, 86 kDa subunit of Ku antigen Antibody, CTC85 Antibody, CTCBF Antibody, DNA repair protein XRCC5 Antibody, G22P2 Antibody, KARP-1 Antibody, Ku autoantigen, 80kDa Antibody, NFIV Antibody, KARP1 Antibody, Ku86 Antibody, KUB2 Antibody, TLAA Antibody, Nuclear factor IV Antibody, KU80 Antibody, Thyroid-lupus autoantigen Antibody


Specifications

Target
Human XRCC5 / Ku80
Host
Mouse
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Ammonium sulfate precipitation
Modifications
Unmodified
Applications
  • IHC
  • Immunofluorescence
  • Western blot (0.5 µg/ml)
  • Immunoprecipitation
  • Flow Cytometry
  • ELISA
  • Gel shift
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
XRCC5 / Ku80 antibody was raised against human B cell nuclei from plasmacytoid 2p68 cells.
Epitope
aa610-705
Specificity
Recognizes the p80 subunit of Ku at 80kD. The epitope maps to between residues 610-705. Species Reactivity: Human and Monkey. Does not react with bovine, Rabbit, Mouse or Rat.
Usage
Suitable for use in ELISA (For coating, Ab can be ordered without BSA), Flow Cytometry, Immunofluorescence, Immunoprecipitation, Western Blot. Not recommended for. Gel Supershift or Immunohistochemistry. Immunoprecipitation: 2 ug antibody/mg protein lysate. Use Protein G. Western Blot: 0.5 ug/ml.
Presentation
10 mM PBS, pH 7.4, 15 mM Sodium Azide, 0.2% BSA
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/20/2018

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