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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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XIAP Antibody (aa163‑230) LS‑C148310
XIAP antibody LS-C148310 is an unconjugated rabbit polyclonal antibody to XIAP from human, mouse, rat and other species. Validated for IHC, IP and WB.
Catalog
Size
Price
LS-C148310-50
50 µl
Unavailable

Popular XIAP Products

Anti-XIAP antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B702 concentration 2 ug/ml.
Species: Human, Mouse
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Antibody
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Applications: IHC, Western blot, Immunoprecipitation
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with BIRC4 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Anti-XIAP antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4870 concentration 10 ug/ml.
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IHC of XIAP in formalin-fixed, paraffin-embedded human breast carcinoma using LS-C148307 at 1:2000. A-A3, successively higher magnifications of the breast carcinoma tissue section. Hematoxylin-Eosin counterstain.
Species: Human, Mouse, Rat, Gerbil
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation

Product Description

XIAP antibody LS-C148310 is an unconjugated rabbit polyclonal antibody to XIAP from human, mouse, rat and other species. Validated for IHC, IP and WB.
About XIAP
Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state. P98170 NM_001167 NP_001158.2

XIAP Antibody, API3 Antibody, BIRC4 Antibody, HILP Antibody, IAP-like protein Antibody, IAP3 Antibody, HIAP-3 Antibody, HIAP3 Antibody, IAP-3 Antibody, ILP Antibody, ILP1 Antibody, MIHA Antibody, X-linked IAP Antibody, XLP2 Antibody


Specifications

Target
Human XIAP
Host
Rabbit
Reactivity
Human, Mouse, Rat, Gerbil (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:1000 - 1:5000)
  • IHC - Frozen
  • Western blot (1:1000 - 1:2000)
  • Immunoprecipitation (1:50 - 1:200)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
XIAP antibody was raised against recombinant BIR2 domain protein fragment of human XIAP. The BIR2 domain used for immunogen corresponds to amino acids 163-230 of human XIAP (Deveraux et al, 1999).
Epitope
aa163-230
Specificity
recognizes epitopes in the BIR2 domain of XIAP. Therefore it can recognize full-length XIAP and XIAP cleavage fragments containing the BIR2 domain. However, XIAP cleavage fragments may be biologically unstable, and therefore cleavage fragments may be difficult to detect.
Presentation
Antiserum, 0.05% sodium azide
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of XIAP in formalin-fixed, paraffin-embedded human prostate carcinoma using LS-C148310 at 1:2000. A, low magnification. A1, high magnification. Hematoxylin-Eosin counterstain.
IHC of XIAP in formalin-fixed, paraffin-embedded human prostate carcinoma using LS-C148310 at 1:2000. A, low magnification. A1, high magnification. Hematoxylin-Eosin counterstain.

Immunohistochemistry

IHC of XIAP in formalin-fixed, paraffin-embedded human prostate carcinoma using LS-C148310 at 1:2000. A, low magnification. A1, high magnification. Hematoxylin-Eosin counterstain.
IHC of XIAP in formalin-fixed, paraffin-embedded human prostate carcinoma using LS-C148310 at 1:2000. A, low magnification. A1, high magnification. Hematoxylin-Eosin counterstain.

Immunohistochemistry

IHC of XIAP in formalin-fixed, paraffin-embedded human prostate carcinoma using LS-C148310 at 1:2000. A, low magnification. A1, high magnification. Hematoxylin-Eosin counterstain.
IHC of XIAP in formalin-fixed, paraffin-embedded human prostate carcinoma using LS-C148310 at 1:2000. A, low magnification. A1, high magnification. Hematoxylin-Eosin counterstain.

Immunohistochemistry

IHC of XIAP in formalin-fixed, paraffin-embedded human prostate carcinoma using LS-C148310 at 1:2000. A, low magnification. A1, high magnification. Hematoxylin-Eosin counterstain.
IHC of XIAP in formalin-fixed, paraffin-embedded human prostate carcinoma using LS-C148310 at 1:2000. A, low magnification. A1, high magnification. Hematoxylin-Eosin counterstain.


Requested From: 
Date Requested: 6/23/2018

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