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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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VISA / MAVS Antibody (aa477‑505) LS‑C164053
MAVS antibody LS-C164053 is an unconjugated rabbit polyclonal antibody to human MAVS (VISA). Validated for WB.
Catalog
Size
Price
LS-C164053-400
400 µl
Unavailable

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Antibody
Species: Human
Applications: IHC, Immunofluorescence, Western blot, Immunoprecipitation, ELISA

Product Description

MAVS antibody LS-C164053 is an unconjugated rabbit polyclonal antibody to human MAVS (VISA). Validated for WB.
About VISA / MAVS
Required for innate immune defense against viruses. Acts downstream of DDX58/RIG-I and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). Peroxisomal and mitochondrial MAVS act sequentially to create an antiviral cellular state. Q7Z434 NM_020746 NP_065797.2

MAVS Antibody, CARDIF Antibody, CARD adaptor inducing IFN-beta Antibody, IPS-1 Antibody, KIAA1271 Antibody, IFN-B promoter stimulator 1 Antibody, VISA Antibody, IPS1 Antibody


Specifications

Target
Human VISA / MAVS
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Blocking Peptide
LS-E2704 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C164053. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa477-505
Specificity
This MAVS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 477-505 amino acids from the C-terminal region of human MAVS.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

MAVS Antibody western blot of HeLa cell line lysates (35 ug/lane). The MAVS antibody detected the MAVS protein (arrow).
MAVS Antibody western blot of HeLa cell line lysates (35 ug/lane). The MAVS antibody detected the MAVS protein (arrow).

Western blot

MAVS Antibody western blot of HeLa cell line lysates (35 ug/lane). The MAVS antibody detected the MAVS protein (arrow).
MAVS Antibody western blot of HeLa cell line lysates (35 ug/lane). The MAVS antibody detected the MAVS protein (arrow).

Western blot

MAVS Antibody western blot of HeLa cell line lysates (35 ug/lane). The MAVS antibody detected the MAVS protein (arrow).
MAVS Antibody western blot of HeLa cell line lysates (35 ug/lane). The MAVS antibody detected the MAVS protein (arrow).

Western blot

MAVS Antibody western blot of HeLa cell line lysates (35 ug/lane). The MAVS antibody detected the MAVS protein (arrow).
MAVS Antibody western blot of HeLa cell line lysates (35 ug/lane). The MAVS antibody detected the MAVS protein (arrow).


Requested From: 
Date Requested: 6/22/2018

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