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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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VISA / MAVS

mitochondrial antiviral signaling protein

Required for innate immune defense against viruses. Acts downstream of DDX58/RIG-I and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). Peroxisomal and mitochondrial MAVS act sequentially to create an antiviral cellular state. Upon viral infection, peroxisomal MAVS induces the rapid interferon-independent expression of defense factors that provide short-term protection, whereas mitochondrial MAVS activates an interferon-dependent signaling pathway with delayed kinetics, which amplifies and stabilizes the antiviral response. May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis.

Gene Name: mitochondrial antiviral signaling protein
Synonyms: MAVS, CARDIF, CARD adaptor inducing IFN-beta, IPS-1, KIAA1271, IFN-B promoter stimulator 1, VISA, IPS1
Target Sequences: NM_020746 NP_065797.2 Q7Z434

Viewing 1-25 of 60 items
VISA / MAVS Antibody - Anti-MAVS antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Rabbit Polyclonal (IgG) to Human VISA / MAVS
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05mg   1mg/ml   $545.00
VISA / MAVS Antibody - Anti-MAVS antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Rabbit Polyclonal (IgG) to Human VISA / MAVS
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05mg   1mg/ml   $425.00
VISA / MAVS Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal (IgG) to Human VISA / MAVS
Mouse, Human
ELISA, IHC-P, WB
Unconjugated
50µl   $425.00
VISA / MAVS Antibody - Cardif is cleaved in liver of a patient infected by the hepatitis C virus. Protein extracts of liver biopsies from a patient with chronic hepatitis C (CHC) and as a control from a patient with alcoholic hepatitis (AH) were run on a SDS-gel and revealed with anti-Cardif (human), mAb (Adri-1) . The arrows indicate endogenous human full-length or cleaved Cardif. . Picture courtesy of Prof. Darius Moradpour, CHUV, Lausanne.
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Mouse Monoclonal [clone Adri-1] (IgG2b) to Human VISA / MAVS
Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
100µg   1mg/ml   $415.00
VISA / MAVS Antibody - Detection of Human MAVS(VISA) by Immunohistochemistry. Sample: FFPE section of human lung carcinoma. Antibody: Affinity purified rabbit anti-MAVS(VISA) used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
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Rabbit Polyclonal (IgG) to Human VISA / MAVS
Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
100µl   0.2mg/ml   $395.00
VISA / MAVS Antibody - MOUSE Mavs Antibody western blot of mouse spleen tissue lysates (35 ug/lane). The MOUSE Mavs antibody detected the MOUSE Mavs protein (arrow).
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Rabbit Polyclonal to Mouse VISA / MAVS
Mouse
WB
Unconjugated
400µl   $325.00
Select
Rabbit Polyclonal (IgG) to Human VISA / MAVS
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100µg   $375.00
VISA / MAVS Antibody
Select
Rabbit Polyclonal (IgG) to Human VISA / MAVS
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
VISA / MAVS Antibody - Western blot analysis of extracts of various cell lines.
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Rabbit Polyclonal (IgG) to Human VISA / MAVS
Mouse, Rat, Human
IF, IHC, IP, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
VISA / MAVS Antibody - Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-MAVS mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120 oC for 3 min. (1:150)
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Mouse Monoclonal [clone OTI8A11] (IgG1) to Human VISA / MAVS
Human
IHC, WB
Unconjugated
100µl   1mg/ml   $345.00
VISA / MAVS Antibody - Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-MAVS mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120 oC for 3 min. (1:150)
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Mouse Monoclonal [clone OTI8A11] (IgG1) to Human VISA / MAVS
Human
IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
VISA / MAVS Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-MAVS mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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Mouse Monoclonal [clone OTI9C4] (IgG1) to Human VISA / MAVS
Human
IHC, WB
Unconjugated
100µl   1mg/ml   $345.00
VISA / MAVS Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-MAVS mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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Mouse Monoclonal [clone OTI9C4] (IgG1) to Human VISA / MAVS
Human
IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
VISA / MAVS Antibody - Immunochemical staining of human MAVS in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
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Rabbit Polyclonal (IgG) to Human VISA / MAVS
Human
ICC, IF, IHC-P
Unconjugated
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
VISA / MAVS Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal (IgG) to Human VISA / MAVS
Human
IHC, IHC-P, WB
Unconjugated
0.1mg   $365.00
VISA / MAVS Antibody - IHC analysis of MAVS using anti-MAVS antibody. MAVS was detected in paraffin-embedded section of human intestinal cancer tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-MAVS Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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Rabbit Polyclonal to Human VISA / MAVS
Human
IHC, WB
Unconjugated
100µg   $355.00
VISA / MAVS Antibody - Fig-1: Western blot analysis of MAVS. Anti-MAVS antibody was used at 0.5 µg/ml on MCF-7 lysate.
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Mouse Monoclonal (IgG2b,k) to Human VISA / MAVS
Human
Flo, WB
Unconjugated
25µg   0.5mg/ml   $225.00; 100µg   0.5mg/ml   $345.00
VISA / MAVS Antibody - Fig-1: Western blot analysis of MAVS. Anti-MAVS antibody was used at 0.5 µg/ml on MCF-7 lysate.
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Mouse Monoclonal (IgG2b,k) to Human VISA / MAVS
Human
Flo, WB
Unconjugated
25µg   0.5mg/ml   $225.00; 100µg   0.5mg/ml   $345.00
VISA / MAVS Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using MAVS Polyclonal Antibody at dilution of 1:30.
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Rabbit Polyclonal (IgG) to Human VISA / MAVS
Mouse, Human
ELISA, IHC, WB
Unconjugated
20µl   0.6mg/ml   $205.00; 60µl   0.6mg/ml   $235.00; 120µl   0.6mg/ml   $295.00; 200µl   0.6mg/ml   $395.00
VISA / MAVS Antibody - Immunohistochemistry-Paraffin: MAVS Antibody (58N3B6) - Formalin-fixed, paraffin-embedded normal human spleen tissue stained with MAVS (IPS-1) antibody (3 ug/ml), peroxidase-conjugate and DAB chromogen.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone 58N3B6] (IgG2b,k) to Human VISA / MAVS
Human
IHC, IHC-P, WB
Unconjugated
100µg   0.5mg/ml   $335.00
Select
Rabbit Polyclonal (IgG) to Human VISA / MAVS
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µg   $575.00
Select
Rabbit Polyclonal to Human VISA / MAVS
Mouse, Human, Monkey
ICC, IP, WB
Unconjugated
100µg   $435.00
Select
Rabbit Polyclonal to Human VISA / MAVS
Human
IF, WB
Unconjugated
100µl   $530.00
Select
Rabbit Polyclonal to Human VISA / MAVS
Human
IHC, WB
Unconjugated
100µl   1mg/ml   $385.00
Select
Rabbit Polyclonal (IgG) to Mouse VISA / MAVS
Mouse
ELISA, WB
Unconjugated
200µl   $590.00

Viewing 1-25 of 60 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).