Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
USP2 Antibody, Deubiquitinating enzyme 2 Antibody, Ubiquitin specific peptidase 2 Antibody, Ubiquitin specific protease 9 Antibody, USP9 Antibody, Ubiquitin specific protease 12 Antibody, Ubiquitin specific protease 2 Antibody, Ubiquitin thioesterase 2 Antibody, UBP41 Antibody
Hydrolase that deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1. Isoform 1 and isoform 4 possess both ubiquitin-specific peptidase and isopeptidase activities. Deubiquitinates MDM2 without reversing MDM2-mediated p53/TP53 ubiquitination and thus indirectly promotes p53/TP53 degradation and limits p53 activity. Has no deubiquitinase activity against p53/TP53. Prevents MDM2-mediated degradation of MDM4.
Western blot of anti-USP2 Antibody in HL60 cell line lysates (35 ug/lane). USP2(arrow) was detected using the purified antibody.
The anti-USP2 Antibody is used in Western blot to detect USP2 in USP2-transfected HeLa cell lysates. Transfection data is kindly provided by Dr. B. Pierrat from the Novartis Institute for Biomedical Research (Basel, Switzerland).
Requested From: United States
Date Requested: 2/27/2017