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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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UBR5 Antibody (Thr14) LS‑C176336
UBR5 antibody LS-C176336 is an unconjugated rabbit polyclonal antibody to UBR5 from human and mouse. Validated for IHC and WB.
Catalog
Size
Price
LS-C176336-100
100 µl
Unavailable

Popular UBR5 Products

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Product Description

UBR5 antibody LS-C176336 is an unconjugated rabbit polyclonal antibody to UBR5 from human and mouse. Validated for IHC and WB.
About UBR5
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity). Involved in maturation and/or transcriptional regulation of mRNA by activating CDK9 by polyubiquitination. May play a role in control of cell cycle progression. May have tumor suppressor function. O95071 NM_015902 NP_056986.2

UBR5 Antibody, DD5 Antibody, EDD Antibody, HHYD Antibody, KIAA0896 Antibody, Progestin-induced protein Antibody, Ubiquitin-protein ligase Antibody, EDD1 Antibody, HYD Antibody, Progestin induced protein Antibody


Specifications

Target
Human UBR5
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
UBR5 antibody was raised against synthetic peptide around Thr14 of human EDD
Epitope
Thr14
Specificity
Human EDD
Presentation
PBS, pH 7.2, 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of EDD (T14) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of EDD (T14) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of EDD (T14) pAb in extracts from A549 cells.
Western blot of EDD (T14) pAb in extracts from A549 cells.

Immunohistochemistry

IHC of EDD (T14) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of EDD (T14) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of EDD (T14) pAb in extracts from A549 cells.
Western blot of EDD (T14) pAb in extracts from A549 cells.

Immunohistochemistry

IHC of EDD (T14) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of EDD (T14) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of EDD (T14) pAb in extracts from A549 cells.
Western blot of EDD (T14) pAb in extracts from A549 cells.

Immunohistochemistry

IHC of EDD (T14) pAb in paraffin-embedded human breast carcinoma tissue.
IHC of EDD (T14) pAb in paraffin-embedded human breast carcinoma tissue.

Western blot

Western blot of EDD (T14) pAb in extracts from A549 cells.
Western blot of EDD (T14) pAb in extracts from A549 cells.


Requested From: 
Date Requested: 6/23/2018

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