UBR5

ubiquitin protein ligase E3 component n-recognin 5

E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity). Involved in maturation and/or transcriptional regulation of mRNA by activating CDK9 by polyubiquitination. May play a role in control of cell cycle progression. May have tumor suppressor function. Regulates DNA topoisomerase II binding protein (TopBP1) in the DNA damage response. Plays an essential role in extraembryonic development. Ubiquitinates acetylated PCK1. Also acts as a regulator of DNA damage response by acting as a suppressor of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of 'Lys-63'-linked histone H2A and H2AX at DNA damage sites, thereby acting as a guard against excessive spreading of ubiquitinated chromatin at damaged chromosomes.

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Products

Antibodies (21)

Type

Primary (21)

Target

UBR5 (21)

Reactivity

Human (21)

Mouse (17)

Rat (1)

Bat (1)

Bovine (2)

Chicken (1)

Dog (1)

Hamster (1)

Horse (1)

Insect (1)

Monkey (1)

Pig (1)

Rabbit (1)

Xenopus (1)

Zebrafish (2)

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Application

IHC (18)

IHC-P (6)

WB (19)

ELISA (7)

IF (1)

IP (4)

Peptide-ELISA (4)

Host

rabbit (19)

goat (1)

sheep (1)

Product Group

IHCPlus (4)

Isotype

IgG (16)

Clonality

polyclonal pc (21)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

PE Conjugated (1)

Unconjugated (16)

Epitope

C-Terminus (6)

aa600-650 (4)

1-80 aa, N-terminal (1)

N-Terminus (1)

Thr14 (1)

aa1-227 (1)

aa1-50 (1)

aa14-63 (1)

aa2749-2799 (1)

aa69-79 (1)

Publications

No (21)

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UBR5 Antibody (aa2749-2799) LS-C289749

Antibody:

UBR5 Rabbit anti-Human Polyclonal (aa2749-2799) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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IHC-plus™ UBR5 Antibody (aa600-650) LS-B5219

(4.0) Rating

Antibody:

UBR5 Rabbit anti-Human Polyclonal (aa600-650) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ UBR5 Antibody (aa1-50) LS-B7629

(4.0) Rating

Antibody:

UBR5 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ UBR5 Antibody (aa14-63) LS-B12486

(4.0) Rating

Antibody:

UBR5 Rabbit anti-Human Polyclonal (aa14-63) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$515

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IHC-plus™ UBR5 Antibody (aa69-79) LS-B5908

(4.0) Rating

Antibody:

UBR5 Goat anti-Human Polyclonal (aa69-79) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Insect, Horse, Bat, Bovine, Rabbit, Mouse, Rat, Hamster, Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µg/$485

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UBR5 Antibody LS-C800387

Antibody:

UBR5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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UBR5 Antibody (aa600-650) LS-C287454

Antibody:

UBR5 Rabbit anti-Human Polyclonal (aa600-650) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

UBR5 Antibody (C-Terminus) LS-C327257

Antibody:

UBR5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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UBR5 Antibody (C-Terminus, Biotin) LS-C244263

Antibody:

UBR5 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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UBR5 Antibody (C-Terminus, FITC) LS-C244264

Antibody:

UBR5 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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UBR5 Antibody (C-Terminus, Azide-free, HRP) LS-C247557

Antibody:

UBR5 Rabbit anti-Human Polyclonal (C-Terminus) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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UBR5 Antibody (C-Terminus, PE) LS-C244265

Antibody:

UBR5 Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

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UBR5 Antibody (C-Terminus, APC) LS-C244262

Antibody:

UBR5 Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• PE
• APC

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • PE
  • APC

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UBR5 Antibody (1-80 aa, N-terminal) LS-C386574

Antibody:

UBR5 Rabbit anti-Human Polyclonal (1-80 aa, N-terminal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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UBR5 Antibody (aa600-650) LS-C290206

Antibody:

UBR5 Rabbit anti-Human Polyclonal (aa600-650) Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

UBR5 Antibody (Thr14) LS-C176336

Antibody:

UBR5 Rabbit anti-Human Polyclonal (Thr14) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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UBR5 Antibody (N-Terminus) LS-C353442

Antibody:

UBR5 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Zebrafish, Pig, Mouse, Dog, Bovine, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

Select

UBR5 Antibody LS-C415964

Antibody:

UBR5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

Select

UBR5 Antibody (aa600-650) LS-C286302

Antibody:

UBR5 Rabbit anti-Human Polyclonal (aa600-650) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

1 µg/$295; 100 µl/$532

Select

UBR5 Antibody LS-C748844

Antibody:

UBR5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

UBR5 Antibody (aa1-227) LS-C143828

Antibody:

UBR5 Sheep anti-Human Polyclonal (aa1-227) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$896

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