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Anti-UBASH3B / STS-1 Antibody (aa564-613) LS-C170311

Catalog	Size	Price
LS-C170311-50	50 µg (1 mg/ml)	Unavailable

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Anti-UBASH3B / STS-1 Antibody LS-C412758

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Anti-UBASH3B / STS-1 Antibody LS-C676671

Antibody:	Rabbit Polyclonal (IgG) to Human UBASH3B / STS-1
Reactivity:	Human
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Format:	Unconjugated

Immunohistochemistry of paraffin-embedded human spleen tissue at dilution 1:100

Antibody:	Rabbit Polyclonal to Rat UBASH3B / STS-1
Reactivity:	Rat, Human, Mouse, Bovine, Guinea pig, Horse, Pig, Rabbit
Application:	Western blot (applications tested for the base form of this product only)
Format:	Unconjugated

This image was taken for the unconjugated form of this product. Other forms have not been tested.

Details

Target:	Rat UBASH3B / STS-1
Host:	Rabbit
Reactivity:	Rat, Human, Mouse, Bovine, Guinea pig, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated. Also available conjugated with Biotin, HRP, FITC.
Purification:	Immunoaffinity purified
Modifications:	Unmodified

Applications

Approved:

Western blot
(applications tested for the base form of this product only)

Specificity and Use

Immunogen:

UBASH3B / STS-1 antibody was raised against synthetic peptide located between aa564-613 of rat Ubash3b (NP_001178721). Percent identity by BLAST analysis: Human, Chimpanzee, Mouse, Rat, Bovine, Rabbit, Horse, Pig, Guinea pig (100%).

Blocking Peptide:

LS-E21737 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C170311. Useful for pre-absorption and neutralization of the antibody's antigen binding site.

Epitope:

aa564-613

Specificity:

Rat UBASH3B

Packaging

Presentation:	Lyophilized from PBS
Reconstitution:	50 µl Distilled water
Storage:	Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
Restrictions:	For research use only.

About UBASH3B / STS-1

Uniprot: Q8TF42 NCBI: NM_032873 NP_116262.2

Synonyms: UBASH3B Antibody, Cbl-interacting protein Sts-1 Antibody, KIAA1959 Antibody, p70 Antibody, STS1 Antibody, TULA-2 Antibody, T-cell ubiquitin ligand 2 Antibody, Cbl-interacting protein p70 Antibody, STS-1 Antibody

Description: Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.

(More About UBASH3B / STS-1)

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Western blot

This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From:
Date Requested: 4/20/2018

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