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Rat UBASH3B / STS-1 | |
Rabbit | |
Rat, Human, Mouse, Bovine, Guinea pig, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity) | |
Polyclonal | |
Unconjugated. Also available conjugated with Biotin, HRP, FITC. | |
Immunoaffinity purified | |
Unmodified |
UBASH3B / STS-1 antibody was raised against synthetic peptide located between aa564-613 of rat Ubash3b (NP_001178721). Percent identity by BLAST analysis: Human, Chimpanzee, Mouse, Rat, Bovine, Rabbit, Horse, Pig, Guinea pig (100%). | ||
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aa564-613 | ||
Rat UBASH3B |
Lyophilized from PBS | |
50 µl Distilled water | |
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles. | |
For research use only. |
UBASH3B Antibody, Cbl-interacting protein Sts-1 Antibody, KIAA1959 Antibody, p70 Antibody, STS1 Antibody, TULA-2 Antibody, T-cell ubiquitin ligand 2 Antibody, Cbl-interacting protein p70 Antibody, STS-1 Antibody
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.
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