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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TS / Thymidylate Synthase Antibody (clone 3A1) LS‑C133503
Thymidylate Synthase antibody LS-C133503 is an unconjugated mouse monoclonal antibody to human Thymidylate Synthase (TS). Validated for ELISA, IF and WB.
Catalog
Size
Price
LS-C133503-100
100 µg
Unavailable

Popular TS / Thymidylate Synthase Products

Antibody
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Anti-TYMS antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1460 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Anti-TYMS antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6165 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
IHC of paraffin-embedded Human tonsil using anti-TYMS mouse monoclonal antibody.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Detection of Human and Mouse TS by Western Blot. Samples: Whole cell lysate (50 ug) from Jurkat, 293T, HeLa, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-TS antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Species: Human, Mouse, Rat, Bovine, Dog, Pig, Rabbit
Applications: Western blot, Immunoprecipitation

Product Description

Thymidylate Synthase antibody LS-C133503 is an unconjugated mouse monoclonal antibody to human Thymidylate Synthase (TS). Validated for ELISA, IF and WB.
About TS / Thymidylate Synthase
Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. P04818 NM_001071 NP_001062.1

TYMS Antibody, HST422 Antibody, Thymidylate synthetase Antibody, TMS Antibody, TS Antibody, Thymidylate synthase Antibody, Tsase Antibody


Specifications

Target
Human TS / Thymidylate Synthase
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal [3A1]
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Applications
  • Immunofluorescence (20 µg/ml)
  • Western blot
  • ELISA
Immunogen
TYMS (AAH13919, 111 a.a. ~ 211 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human TYMS
Usage
Sandwich ELISA: Recombinant protein. Western Blot: Cell lysate, Transfected lysate, Recombinant protein.
Presentation
PBS, pH 7.4
Storage
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunofluorescence

Immunofluorescence of monoclonal antibody to TYMS on HeLa cell. [antibody concentration 20 ug/ml]
Immunofluorescence of monoclonal antibody to TYMS on HeLa cell. [antibody concentration 20 ug/ml]

Western blot

Western blot of TYMS expression in transfected 293T cell line by TYMS monoclonal antibody (M01), clone 3A1.
Western blot of TYMS expression in transfected 293T cell line by TYMS monoclonal antibody (M01), clone 3A1.

Western blot

TYMS monoclonal antibody (M01), clone 3A1 Western blot of TYMS expression in HeLa.
TYMS monoclonal antibody (M01), clone 3A1 Western blot of TYMS expression in HeLa.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged TYMS is approximately 0.03 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged TYMS is approximately 0.03 ng/ml as a capture antibody.

Immunofluorescence

Immunofluorescence of monoclonal antibody to TYMS on HeLa cell. [antibody concentration 20 ug/ml]
Immunofluorescence of monoclonal antibody to TYMS on HeLa cell. [antibody concentration 20 ug/ml]

Western blot

Western blot of TYMS expression in transfected 293T cell line by TYMS monoclonal antibody (M01), clone 3A1.
Western blot of TYMS expression in transfected 293T cell line by TYMS monoclonal antibody (M01), clone 3A1.

Western blot

TYMS monoclonal antibody (M01), clone 3A1 Western blot of TYMS expression in HeLa.
TYMS monoclonal antibody (M01), clone 3A1 Western blot of TYMS expression in HeLa.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged TYMS is approximately 0.03 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged TYMS is approximately 0.03 ng/ml as a capture antibody.

Immunofluorescence

Immunofluorescence of monoclonal antibody to TYMS on HeLa cell. [antibody concentration 20 ug/ml]
Immunofluorescence of monoclonal antibody to TYMS on HeLa cell. [antibody concentration 20 ug/ml]

Western blot

Western blot of TYMS expression in transfected 293T cell line by TYMS monoclonal antibody (M01), clone 3A1.
Western blot of TYMS expression in transfected 293T cell line by TYMS monoclonal antibody (M01), clone 3A1.

Western blot

TYMS monoclonal antibody (M01), clone 3A1 Western blot of TYMS expression in HeLa.
TYMS monoclonal antibody (M01), clone 3A1 Western blot of TYMS expression in HeLa.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged TYMS is approximately 0.03 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged TYMS is approximately 0.03 ng/ml as a capture antibody.

Immunofluorescence

Immunofluorescence of monoclonal antibody to TYMS on HeLa cell. [antibody concentration 20 ug/ml]
Immunofluorescence of monoclonal antibody to TYMS on HeLa cell. [antibody concentration 20 ug/ml]

Western blot

Western blot of TYMS expression in transfected 293T cell line by TYMS monoclonal antibody (M01), clone 3A1.
Western blot of TYMS expression in transfected 293T cell line by TYMS monoclonal antibody (M01), clone 3A1.

Western blot

TYMS monoclonal antibody (M01), clone 3A1 Western blot of TYMS expression in HeLa.
TYMS monoclonal antibody (M01), clone 3A1 Western blot of TYMS expression in HeLa.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged TYMS is approximately 0.03 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged TYMS is approximately 0.03 ng/ml as a capture antibody.


Requested From: 
Date Requested: 6/23/2018

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