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Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) By similarity. May also be activated by intracellular calcium store depletion.
Gene Name: | transient receptor potential cation channel, subfamily C, member 7 |
Family/Subfamily: | Ion Channel , Calcium channel - TRP |
Synonyms: | TRPC7, KNP3, Trrp8, Transient receptor protein 7, TRP-7, TRP7, HTRP7 |
Target Sequences: | NM_020389 NP_065122.1 Q9HCX4 |
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