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Anti-TPP1 / CLN2 Antibody (aa201-215) LS-C102868

Catalog Size Price
LS-C102868-100 100 µg Unavailable

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100% Guaranteed
Goat Polyclonal to Human TPP1 / CLN2
Human, Monkey
Western blot, ELISA


Human TPP1 / CLN2
Human, Monkey (tested or 100% immunogen sequence identity)
Bovine (at least 90% immunogen sequence identity)
Immunoaffinity purified


  • Western blot (0.3 - 1 µg/ml)
  • ELISA (1:4000)

Specificity and Use

TPP1 / CLN2 antibody was raised against synthetic peptide C-TPSVIRKRYNLTSQD from an internal region of human TPP1 (NP_000382.3). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Monkey (100%); Bovine (93%); Marmoset, Dog, Horse, Rabbit, Opossum (87%); Elephant, Panda, Bat (80%).
LS-E27147 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C102868. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human TPP1.
Peptide ELISA: antibody detection limit dilution 1:4000. Western blot: Approx 65 kDa band observed in Human Placenta lysates (calculated MW of 61.2 kDa according to NP_000382.3). Recommended concentration: 0.3-1 ug/ml.


Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About TPP1 / CLN2

O14773 NM_000391 NP_000382.3

TPP1 Antibody, CLN2 Antibody, GIG1 Antibody, LPIC Antibody, LINCL Antibody, TPP-I Antibody, Tripeptidyl aminopeptidase Antibody, Tripeptidyl peptidase I Antibody, Tripeptidyl-peptidase 1 Antibody, Tripeptidyl-peptidase I Antibody, TPP-1 Antibody, Growth-inhibiting protein 1 Antibody

TPP1 / CLN2 is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification.

Western blot

TPP1 antibody (0.3 ug/ml) staining of Human Placenta lysate (35 ug protein/ml in RIPA buffer) with (B) and without (A) blocking with the immunizing peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
TPP1 antibody (0.3 ug/ml) staining of Human Placenta lysate (35 ug protein/ml in RIPA buffer) with (B) and without (A) blocking with the immunizing peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

Requested From: 
Date Requested: 4/24/2018

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