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Anti-TNFRSF10B / Killer / DR5 Antibody (C-Terminus) IHC-plus™ LS-B136

Note: This antibody replaces LS-C286, LS-C57026, LS-C42803, LS-C14917
Catalog Size Price
LS-B136-50 50 µg (1 mg/ml) Unavailable

Most Popular TNFRSF10B / Killer / DR5 Antibodies

Anti-TNFRSF10B / Killer / DR5 Antibody (C-Terminus) IHC-plus™ LS-B136
Rabbit Polyclonal to Human TNFRSF10B / Killer / DR5
Human, Mouse
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-TNFRSF10B / Killer / DR5 Antibody (aa388-407) IHC-plus™ LS-B2074
Rabbit Polyclonal (IgG) to Human TNFRSF10B / Killer / DR5
Human
IHC - Paraffin, ICC, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image
Anti-TNFRSF10B / Killer / DR5 Antibody (aa380-398) IHC-plus™ LS-B5086
Rabbit Polyclonal (IgG) to Human TNFRSF10B / Killer / DR5
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-TNFRSF10B / Killer / DR5 Antibody (aa203-411, clone 1B9) LS-C340229
Mouse Monoclonal [clone 1B9] (IgG1) to Human TNFRSF10B / Killer / DR5
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-TNFRSF10B / Killer / DR5 Antibody (clone HS201) IHC-plus™ LS-B13479
Mouse Monoclonal [clone HS201] (IgG1) to Human TNFRSF10B / Killer / DR5
Human
IHC - Paraffin, ICC, Immunoprecipitation, Flow Cytometry, Functional Assay
Unconjugated
Immunohistochemistry - Paraffin Image

100% Guaranteed
Rabbit Polyclonal to Human TNFRSF10B / Killer / DR5
Human, Mouse
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Unconjugated

Details

Human TNFRSF10B / Killer / DR5
Rabbit
Human, Mouse (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 - 10 µg/ml)
  • ICC (5 µg/ml)
  • Immunofluorescence (10 µg/ml)
  • Western blot (2 µg/ml)

Specificity and Use

A peptide corresponding to amino acids near the carboxy terminus of human DR5 precursor .
LS-E29870 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-B136. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
C-Terminus
This antibody has no cross reaction to DR4.
Immunohistochemistry: LS-B136 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B136 was determined to be 5-10 ug/ml.

Packaging

PBS, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About TNFRSF10B / Killer / DR5

O14763 NM_147187 Q6FH58

TNFRSF10B Antibody, Cytotoxic TRAIL receptor-2 Antibody, CD262 antigen Antibody, DR5 Antibody, Death receptor 5 Antibody, KILLER Antibody, TRAIL-R2 Antibody, TRICK2B Antibody, TRAILR2 Antibody, TRICK2A Antibody, TRICKB Antibody, TRICK2 Antibody, CD262 Antibody, Fas-like protein Antibody, TRAIL receptor 2 Antibody, ZTNFR9 Antibody

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family. DR4 was recently identified as the receptor for TRAIL. A novel death domain containing receptor for TRAIL was more recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several groups independently.

Immunohistochemistry

Immunohistochemistry
Anti-DR5 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B136 concentration 10 ug/ml.

Immunocytochemistry

Immunocytochemistry
Immunocytochemistry of DR5 in HeLa cells with DR5 antibody at 5 ug/ml.

Immunofluorescence

Immunofluorescence
Immunofluorescence of DR5 in HeLa cells with DR5 antibody at 20 ug/ml.

Western blot

Western blot
Western blot of DR5 in HeLa (H) and K562 (K) cell lysates with DR5 antibody at 2 ug/ml.

Requested From: 
Date Requested: 8/23/2017

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