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Anti-TNFRSF10B / Killer / DR5 Antibody (aa388-407) IHC-plus™ LS-B2074

Note: This antibody replaces LS-C669

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TNFRSF10B / Killer / DR5 Antibodies

Anti-TNFRSF10B / Killer / DR5 Antibody (C-Terminus) IHC-plus™ LS-B136
Rabbit Polyclonal to Human TNFRSF10B / Killer / DR5
Human, Mouse
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-TNFRSF10B / Killer / DR5 Antibody (aa388-407) IHC-plus™ LS-B2074
Rabbit Polyclonal (IgG) to Human TNFRSF10B / Killer / DR5
Human
IHC - Paraffin, ICC, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image
Anti-TNFRSF10B / Killer / DR5 Antibody (aa380-398) IHC-plus™ LS-B5086
Rabbit Polyclonal (IgG) to Human TNFRSF10B / Killer / DR5
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human TNFRSF10B / Killer / DR5
Human
IHC - Paraffin, ICC, Western blot, Flow Cytometry
Unconjugated

Details

Human TNFRSF10B / Killer / DR5
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • ICC
  • Western blot (1:500 - 1:1000)
  • Flow Cytometry

Specificity and Use

TNFRSF10B / Killer / DR5 antibody was raised against a peptide corresponding to amino acids 388 to 407 (isoform 2) of human DR5 precursor (1,2). The same sequence is found in isoform 1 at amino acids 417-436.
aa388-407
A peptide corresponding to amino acids 388 to 407 (isoform 2) of human DR5 precursor. The same sequence is found in isoform 1 at amino acids 417-436.
Immunohistochemistry: LS-B2074 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2074 was determined to be 10 ug/ml.

Packaging

PBS, 0.05% BSA, 0.05% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About TNFRSF10B / Killer / DR5

O14763 NM_147187 Q6FH58

TNFRSF10B Antibody, Cytotoxic TRAIL receptor-2 Antibody, CD262 antigen Antibody, DR5 Antibody, Death receptor 5 Antibody, KILLER Antibody, TRAIL-R2 Antibody, TRICK2B Antibody, TRAILR2 Antibody, TRICK2A Antibody, TRICKB Antibody, TRICK2 Antibody, CD262 Antibody, Fas-like protein Antibody, TRAIL receptor 2 Antibody, ZTNFR9 Antibody

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family. DR4 was recently identified as the receptor for TRAIL. A novel death domain containing receptor for TRAIL was more recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several groups independently.

Immunohistochemistry

Immunohistochemistry
Anti-DR5 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2074 concentration 10 ug/ml.

Western blot

Western blot
Western blot of 20 ug of whole cell lysates from HL60 cells with anti-DR5 at 5 ug/ml?dilution.

Requested From: United States
Date Requested: 12/7/2016

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