LSBio The Immunohistochemistry Antibody Company
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All Kits
  • Sandwich ELISA Kits
  • Competitive EIA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Direct ELISA Kits
  • Functional ELISA Kits
  • Phospho-Specific ELISA Kits
  • Custom ELISA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Other
  • Blocking Peptides
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Publications
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Anti-TLK1 Antibody (C-Terminus) LS-C10636

Ordering

Wt. Vol. Conc. Price
100 µg - - $495
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TLK1 Antibodies

Anti-TLK1 Antibody (aa730-779) IHC-plus™ LS-B9860
Rabbit Polyclonal (IgG) to Human TLK1
Human, Mouse
IHC - Paraffin, Immunofluorescence, ELISA
Unconjugated
Immunohistochemistry Image
Anti-TLK1 Antibody (aa701-728, APC) LS-C271585
Rabbit Polyclonal (IgG) to Mouse TLK1
Mouse
Western blot, ELISA
APC Conjugated
Anti-TLK1 Antibody (aa701-728, Azide-free, HRP) LS-C271588
Rabbit Polyclonal (IgG) to Mouse TLK1
Mouse
Western blot, ELISA
HRP Conjugated, Azide-free

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human TLK1
Human
IHC, Western blot, Immunoprecipitation, ELISA, Functional Assay
Unconjugated

Details

Human TLK1
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC (2 µg/ml)
  • Western blot (1 - 2 µg/ml)
  • Immunoprecipitation
  • ELISA (0.1 - 1 µg/ml)
  • Functional Assay

Specificity and Use

TLK1 antibody was raised against a synthetic peptide derived from a sequence located near the C-terminus of the human Tlk-1 protein.
C-Terminus
Specific for the ~85kD Tlk1 (Tousled-like kinase 1) protein. It does not cross-react with the related Tlk2 protein. Antibody specificity was confirmed by Western blot with epitope-tagged Tlk1 and Tlk2 proteins, Western blot and immunoprecipitation with HeLa cell lysates and by immunoprecipitation with in vitro transcribed and translated Tlk1 and Tlk2. A nuclear localization of this protein is observed by immunohistochemistry with HeLa cells. Species cross-reactivity: human.
Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry. ELISA: 0.1-1.0 ug/ml. Immunohistochemistry: 2 ug/ml. Immunoprecipitation: 5 ug/IP reaction. (native and IP-kinase assay). Western Blot: 1-2 ug/ml.

Packaging

PBS, pH 7.4, 05% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About TLK1

Q9UKI8 NM_012290 NP_036422.3

TLK1 Antibody, KIAA0137 Antibody, Tousled-like kinase 1 Antibody, Snare kinase snak Antibody, PKU-beta Antibody, SNARE protein kinase SNAK Antibody

Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs.

Requested From: United States
Date Requested: 12/4/2016

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn
Copyright © 2016 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number