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Anti-THRA / THR Alpha Antibody (N-Terminus) LS-C60119

Ordering

Wt. Vol. Conc. Price
100 µg - - $405
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular THRA / THR Alpha Antibodies

Anti-THRA / THR Alpha Antibody (Ligand-binding Domain) IHC-plus™ LS-A6196
Rabbit Polyclonal to Human THRA / THR Alpha
Human, Monkey
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-THRA / THR Alpha Antibody (aa325-374) LS-C134993
Rabbit Polyclonal to Rat THRA / THR Alpha
Rat, Human, Monkey, Mouse, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep, Zebrafish
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human THRA / THR Alpha
Human
Western blot, ELISA
Unconjugated

Details

Human THRA / THR Alpha
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (1:1000)
  • ELISA (1:650000)

Specificity and Use

THRA / THR Alpha antibody was raised against synthetic peptide corresponding to a region near the amino terminus of human THRA isoform 1 protein.
N-Terminus
human THRA protein. A BLAST analysis was used to suggest cross- reactivity with THRA from mouse, human and rat based on a 100% homology with the immunizing sequence. Cross-reactivity with THRA from other sources has not been determined
This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~55 kD in size corresponding to THRA by western blotting in the appropriate cell lysate or extract. This antibody is capable of detecting transiently transfected THRA. Detection of endogenous THRA must be optimized by the end user.

Packaging

0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Long term: -20°C; Short term: -20°C
For research use only.

About THRA / THR Alpha

P10827 NM_003250 NP_003241.2

THRA Antibody, AR7 Antibody, C-ERBA-1 Antibody, C-erbaalpha Antibody, EAR-7.1/EAR-7.2 Antibody, ERB-T-1 Antibody, ERBA1 Antibody, EAR-7 Antibody, ERBA-related 7 Antibody, HTR alpha 1 Antibody, HTR alpha 2 Antibody, THRA1 Antibody, Thyroid hormone receptor alpha Antibody, T3R Antibody, Tralpha2 Antibody, Triiodothyronine receptor Antibody, V-erbA-related protein 7 Antibody, Thyroid hormone receptor Antibody, Tralpha1 Antibody, NR1A1 Antibody, THRA3 Antibody, C-erbA-alpha Antibody, CHNG6 Antibody, EAR7 Antibody, ERBA Antibody, Erba-alpha Antibody, THRA2 Antibody, TR alpha Antibody, Tralpha Antibody

Thyroid hormone receptor alpha (TR alpha), a NR1 Thyroid Hormone-Like Receptor, mediates the diverse actions of thyroid hormone in development, differentiation, and metabolism. Four protein isoforms are encoded by the same TR alpha genomic locus: TR alpha1 (410 aa) (Nakai et al. 1988), TR alpha2 (490 aa) ( Nakai et al. 1988), TR deltaalpha1 (~154 aa), and TR deltaalpha2 (~237 aa); however, only TR alpha1 is able to bind the ligand ( Lazar et al. 1988).

Western blot

Western blot
Anti-THRA Antibody - Western Blot. Western blot of affinity purified anti-THRA antibody shows detection of purified recombinant THRA (lane 1) and THRA present in a 293 cell lysate after transient transfection with THRA (lane 3). No staining is evident in lysates from mock-transfected 293 cells (lane 2). Endogenous THRA is not detected in mouse brain whole cell lysate (lane 4). Nuclear extracts may be required to detect endogenous THRA as the protein localizes within the nucleus. The band at ~55 kD, indicated by the arrowhead, corresponds to THRA. Personal communication, S. Cheng and H. Ying, NCI, Bethesda, MD.
 

Requested From: United States
Date Requested: 12/10/2016

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