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Anti-TDP-43 / TARDBP Antibody LS-C56457

Note: This antibody replaces LS-C56893
Catalog Size Price
LS-C56457-100 100 µg Unavailable

Most Popular TDP-43 / TARDBP Antibodies

Anti-TDP-43 / TARDBP Antibody (aa337-386) LS-C30991
Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Rabbit
IHC, IHC - Frozen, Western blot
TARDBP antibody LS-C30991 was used in IHC to stain formalin-fixed, paraffin-embedded human liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-TDP-43 / TARDBP Antibody (Internal) IHC-plus™ LS-B2223
Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Human, Mouse, Rat
IHC, IHC - Paraffin, Western blot
Anti-TARDBP antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2223 concentration 5 ug/ml.
Anti-TDP-43 / TARDBP Antibody (aa1-260, clone K1B8) IHC-plus™ LS-B2957
Mouse Monoclonal [clone K1B8] (IgG1,k) to Human TDP-43 / TARDBP
IHC, IHC - Paraffin, Western blot, ELISA
Anti-TARDBP antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2957 concentration 10 ug/ml.
Anti-TDP-43 / TARDBP Antibody (clone 2E2-D3) IHC-plus™ LS-B4521
Mouse Monoclonal [clone 2E2-D3] (IgG1,k) to Human TDP-43 / TARDBP
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA, RNA interference
Anti-TARDBP antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4521 concentration 5 ug/ml.
Anti-TDP-43 / TARDBP Antibody (C-Terminus) LS-C144920
Rabbit Polyclonal to Mouse TDP-43 / TARDBP
IHC, Western blot

100% Guaranteed
Rabbit Polyclonal to Human TDP-43 / TARDBP
Human, Mouse, Rat
Western blot


Human TDP-43 / TARDBP
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Affinity purified


Western blot (0.5 - 1 µg/ml)

Specificity and Use

TDP-43 / TARDBP antibody was raised against an 18 amino acid peptide located near the centre of human TDP43.
Recognizes TAR DNA-binding protein 43 (TDP43), a 43 kD protein that is located in the nucleus. TDP43 is ubiquitously expressed in human tissue, with high levels detected in the lung, pancreas, spleen, placenta and genital tract. AHP1443 recognizes the longer of the two TDP43 isoforms identified. TDP43 is transcriptional repressor protein that binds to chromosomally integrated TAR DNA and represses HIV-1 Transcription. Studies also suggest that TDP43 is involved in the regulation of cystic fibrosis transmembrane conductance regulator (CFTR) splicing, probably through the association with UG repeats at the 3a€™ splice site. A pathologic form of TDP43 has also been identified, which is a major disease protein in ubiquitinated inclusions characteristic of a range of neurodegenerative diseases.
Western Blot: LS-C56457 detects a band of approximately 43kD in L1210 cell lysate.


PBS, 0.02% sodium azide.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About TDP-43 / TARDBP

Q13148 NM_007375 NP_031401.1

TARDBP Antibody, ALS10 Antibody, TAR DNA-binding protein-43 Antibody, TDP-43 Antibody, TAR DNA binding protein Antibody, TAR DNA-binding protein 43 Antibody, TDP43 Antibody

DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division.

Requested From: 
Date Requested: 5/20/2018

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