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Anti-TDP-43 / TARDBP Antibody (aa337-386) LS-C30991

Ordering

Wt. Vol. Conc. Price
100 µg 100 µl 1 mg/ml $325
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TDP-43 / TARDBP Antibodies

Anti-TDP-43 / TARDBP Antibody (clone 2E2-D3) IHC-plus™ LS-B4521
Mouse Monoclonal [clone 2E2-D3] (IgG1,k) to Human TDP-43 / TARDBP
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA, RNA interference
Unconjugated
Immunohistochemistry Image
Anti-TDP-43 / TARDBP Antibody LS-C124633
Rat Monoclonal (IgG2a,k) to Human TDP-43 / TARDBP
Human
IHC, Western blot, ELISA
Unconjugated
Anti-TDP-43 / TARDBP Antibody (C-Terminus) LS-C144920
Rabbit Polyclonal to Mouse TDP-43 / TARDBP
Mouse
IHC, Western blot
Unconjugated

100% Guaranteed 100% Guaranteed Publications Publications (1)
Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Rabbit
IHC - Frozen, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human TDP-43 / TARDBP
Rabbit
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Rabbit (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with Biotin, HRP, FITC.
Protein A purified
Unmodified

Applications

  • IHC - Frozen
  • Western blot (1.25 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

TDP-43 / TARDBP antibody was raised against synthetic peptide located between aa337-386 of human TARDBP (Q13148, NP_031401). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Dog, Bovine, Bat, Rabbit, Horse, Opossum, Guinea pig, Platypus (100%).
aa337-386
Human TARDBP

Packaging

Lyophilized from PBS with 2% sucrose
100 µl Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

Publications (1)

1
Sialylation and muscle performance: sialic acid is a marker of muscle ageing. Hanisch F, Weidemann W, Gro[Character df]mann M, Joshi PR, Holzhausen HJ, Stoltenburg G, Weis J, Zierz S, Horstkorte R. PloS one. 2013 8:e80520. [Full Text Article] [PubMed:24349002] [PMC:PMC3859654]

About TDP-43 / TARDBP

Q13148 NM_007375 NP_031401.1

TARDBP Antibody, ALS10 Antibody, TAR DNA-binding protein-43 Antibody, TDP-43 Antibody, TAR DNA binding protein Antibody, TAR DNA-binding protein 43 Antibody, TDP43 Antibody

DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division.

Immunohistochemistry

Immunohistochemistry
TARDBP antibody LS-C30991 was used in IHC to stain formalin-fixed, paraffin-embedded human liver. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

Immunohistochemistry
TARDBP antibody LS-C30991 was used in IHC to stain formalin-fixed, paraffin-embedded human heart. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
A: Marker, B: Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/6/2016

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