Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
TCF12 Antibody, BHLHb20 Antibody, E-box-binding protein Antibody, HEB Antibody, HsT17266 Antibody, HTF4 Antibody, TCF-12 Antibody, Transcription factor 12 Antibody, Transcription factor HTF-4 Antibody, DNA-binding protein HTF4 Antibody
TCF12 / HEB is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins.
Immunoperoxidase of monoclonal antibody to TCF12 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 1 ug/ml]
Western blot of TCF12 expression in transfected 293T cell line by TCF12 monoclonal antibody (M01), clone 2E9.
TCF12 monoclonal antibody (M01), clone 2E9 Western blot of TCF12 expression in Jurkat.
Western blot of TCF12 over-expressed 293 cell line, cotransfected with TCF12 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with TCF12 monoclonal antibody, clone 2E9. GAPDH ( 36.1 kD ) used as specificity.