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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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STXBP1 / MUNC18‑1 Antibody (phospho‑Ser313) LS‑C199288
MUNC18-1 antibody LS-C199288 is an unconjugated rabbit polyclonal antibody to MUNC18-1 (STXBP1) from human, mouse and rat. Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C199288-50
50 µl
Unavailable
LS-C199288-100
100 µl
Unavailable

Popular STXBP1 / MUNC18-1 Products

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Product Description

MUNC18-1 antibody LS-C199288 is an unconjugated rabbit polyclonal antibody to MUNC18-1 (STXBP1) from human, mouse and rat. Validated for Peptide-ELISA and WB.
About STXBP1 / MUNC18-1
May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. P61764 NM_003165 NP_003156.1

STXBP1 Antibody, EIEE4 Antibody, HUNC18 Antibody, MUNC18-1 Antibody, N-Sec1 Antibody, NSEC1 Antibody, Protein unc-18 homolog 1 Antibody, Protein unc-18 homolog A Antibody, UNC18 Antibody, Unc18-1 Antibody, p67 Antibody, RBSEC1 Antibody, Unc-18A Antibody, Munc18 Antibody, Neuronal SEC1 Antibody, Syntaxin binding protein 1 Antibody, Syntaxin-binding protein 1 Antibody, UNC18A Antibody


Specifications

Target
Human STXBP1 / MUNC18-1
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:1000)
Immunogen
Synthetic peptide derived from human MUNC-18a around the phosphorylation site of Ser313.
Epitope
pSer313
Specificity
MUNC-18a (Phospho-Ser313) Antibody detects endogenous levels of MUNC-18a only when phosphorylated at serine313.
Presentation
PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
Store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of extracts from COS7 cells treated with PMA 125ng/ml 30', using MUNC-18a (Phospho-Ser313) Antibody. The lane on the right was incubated with synthetic peptide.
Western blot of extracts from COS7 cells treated with PMA 125ng/ml 30', using MUNC-18a (Phospho-Ser313) Antibody. The lane on the right was incubated with synthetic peptide.

Western blot

Western blot of extracts from COS7 cells treated with PMA 125ng/ml 30', using MUNC-18a (Phospho-Ser313) Antibody. The lane on the right was incubated with synthetic peptide.
Western blot of extracts from COS7 cells treated with PMA 125ng/ml 30', using MUNC-18a (Phospho-Ser313) Antibody. The lane on the right was incubated with synthetic peptide.

Western blot

Western blot of extracts from COS7 cells treated with PMA 125ng/ml 30', using MUNC-18a (Phospho-Ser313) Antibody. The lane on the right was incubated with synthetic peptide.
Western blot of extracts from COS7 cells treated with PMA 125ng/ml 30', using MUNC-18a (Phospho-Ser313) Antibody. The lane on the right was incubated with synthetic peptide.

Western blot

Western blot of extracts from COS7 cells treated with PMA 125ng/ml 30', using MUNC-18a (Phospho-Ser313) Antibody. The lane on the right was incubated with synthetic peptide.
Western blot of extracts from COS7 cells treated with PMA 125ng/ml 30', using MUNC-18a (Phospho-Ser313) Antibody. The lane on the right was incubated with synthetic peptide.


Requested From: 
Date Requested: 6/18/2018

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