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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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STXBP1 / MUNC18-1

syntaxin binding protein 1

May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.

Gene Name: syntaxin binding protein 1
Synonyms: STXBP1, EIEE4, HUNC18, MUNC18-1, N-Sec1, NSEC1, Protein unc-18 homolog 1, Protein unc-18 homolog A, UNC18, Unc18-1, p67, RBSEC1, Unc-18A, Munc18, Neuronal SEC1, Syntaxin binding protein 1, Syntaxin-binding protein 1, UNC18A
Target Sequences: NM_003165 NP_003156.1 P61764

Filtered By: None
Target
STXBP1 / MUNC18-1 (39)
Reactivity
Human (39)
Mouse (29)
Rat (21)
Bat (6)
Bovine (9)
Chicken (5)
Chimpanzee (3)
Dog (8)
Guinea pig (5)
Hamster (1)
Horse (5)
Monkey (6)
Non-Human Primate (1)
Orangutan (3)
Pig (5)
Rabbit (6)
Sheep (2)
Xenopus (5)
Zebrafish (4)
Application
IHC (15)
IHC-P (7)
WB (32)
ELISA (14)
ICC (1)
IF (5)
Peptide-ELISA (3)
Host
rabbit (33)
mouse (4)
goat (2)
Isotype
IgG (26)
IgG2a,k (1)
IgG2b,k (3)
Clonality
monoclonal mc (4)
polyclonal pc (35)
Clone
1B9 (3)
6D1 (1)
Format
AP Conjugated (1)
APC Conjugated (1)
Biotin Conjugated (4)
FITC Conjugated (3)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (25)
Epitope
aa504-553 (4)
250-330 aa (2)
Internal (2)
aa1-603 (1)
aa184-216 (1)
aa279-328 (1)
aa591-603 (1)
aa80-226 (1)
pSer241 (1)
pSer313 (1)
pSer515 (1)
pThr574 (1)
Publications
No (39)
Showing 1-25 of 39 results

STXBP1 / MUNC18-1 Antibody (clone 6D1) IHC-plus™ LS-B5542
Mouse Monoclonal [clone 6D1] (IgG2a,k) to Human STXBP1 / MUNC18-1
Mouse, Human
ELISA IHC IHC-P WB
Unconjugated
50µg 0.41mg/ml  $485.00
Anti-STXBP1 antibody IHC of human pancreas, islets of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-STXBP1 antibody IHC of human brain, neuropil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-STXBP1 antibody IHC of human pancreas, islets of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-STXBP1 antibody IHC of human brain, neuropil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

STXBP1 / MUNC18-1 Antibody (Internal) IHC-plus™ LS-B14632
Rabbit Polyclonal to Human STXBP1 / MUNC18-1
Mouse, Bovine, Rat, Human
ICC IF IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $425.00
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunofluorescent analysis of p67 staining in Jurkat cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunofluorescent analysis of p67 staining in Jurkat cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

STXBP1 / MUNC18-1 Antibody (aa591-603) IHC-plus™ LS-B4446
Goat Polyclonal to Human STXBP1 / MUNC18-1
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Bat, Human, Monkey
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-STXBP1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Antibody (0.1 ug/ml) staining of Human Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Anti-STXBP1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Antibody (0.1 ug/ml) staining of Human Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

STXBP1 / MUNC18-1 Antibody (aa279-328) IHC-plus™ LS-B5576
Rabbit Polyclonal (IgG) to Human STXBP1 / MUNC18-1
Mouse, Rat, Human
IF IHC IHC-P Peptide-ELISA
Unconjugated
50µl 1mg/ml  $425.00
Anti-STXBP1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Immunofluorescence analysis of NIH/3T3 cells, using MUNC-18a Antibody. The picture on the right is blocked with the synthesized peptide.
Anti-STXBP1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Immunofluorescence analysis of NIH/3T3 cells, using MUNC-18a Antibody. The picture on the right is blocked with the synthesized peptide.

STXBP1 / MUNC18-1 Antibody (Internal) LS-C94840
Rabbit Polyclonal (IgG) to Human STXBP1 / MUNC18-1
Mouse, Rat, Human
IHC WB
Unconjugated
500µg 500µl 1mg/ml  $325.00

STXBP1 / MUNC18-1 Antibody LS-C671798
Rabbit Polyclonal (IgG) to Human STXBP1 / MUNC18-1
Human
ELISA IF IHC IHC-P WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image of paraffin-embedded human melanoma cancer at a dilution of 1:100
Immunofluorescent analysis of Hela cells at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunohistochemistry image of paraffin-embedded human melanoma cancer at a dilution of 1:100
Immunofluorescent analysis of Hela cells at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

STXBP1 / MUNC18-1 Antibody (250-330 aa) LS-C386587
Rabbit Polyclonal (IgG) to Human STXBP1 / MUNC18-1
Mouse, Rat, Human
ELISA IF IHC
Unconjugated
100µl 1mg/ml  $265.00

STXBP1 / MUNC18-1 Antibody LS-C405369
Rabbit Polyclonal (IgG) to Human STXBP1 / MUNC18-1
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human brain using STXBP1 Polyclonal Antibody at dilution of 1:20.
Immunohistochemistry of Human colon cancer using STXBP1 Polyclonal Antibody at dilution of 1:20.
Immunohistochemistry of Human brain using STXBP1 Polyclonal Antibody at dilution of 1:20.
Immunohistochemistry of Human colon cancer using STXBP1 Polyclonal Antibody at dilution of 1:20.

STXBP1 / MUNC18-1 Antibody (aa184-216) LS-C408031
Rabbit Polyclonal to Human STXBP1 / MUNC18-1
Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Pig, Horse, Bat, Human
IHC IHC-P WB
Unconjugated
100µg  $355.00
Munc18-1 antibody IHC-paraffin. IHC(P): Mouse Brain Tissue.
Munc18-1 antibody IHC-paraffin. IHC(P): Rat Brain Tissue.
Munc18-1 antibody IHC-paraffin. IHC(P): Mouse Brain Tissue.
Munc18-1 antibody IHC-paraffin. IHC(P): Rat Brain Tissue.

STXBP1 / MUNC18-1 Antibody LS-C490493
Rabbit Polyclonal (IgG) to Human STXBP1 / MUNC18-1
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
100µg  $365.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

STXBP1 / MUNC18-1 Antibody (phospho-Thr574) LS-C153567
Rabbit Polyclonal to Human STXBP1 / MUNC18-1
Mouse, Rat, Human
ELISA IF WB
Unconjugated
100µg 100µl 1mg/ml  $315.00

STXBP1 / MUNC18-1 Antibody LS-C753094
Rabbit Polyclonal (IgG) to Human STXBP1 / MUNC18-1
Human
ELISA IHC WB
Unconjugated
100µg  $355.00

STXBP1 / MUNC18-1 Antibody LS-C753095
Rabbit Polyclonal (IgG) to Human STXBP1 / MUNC18-1
Human
ELISA IHC WB
Unconjugated
100µg  $355.00

STXBP1 / MUNC18-1 Antibody LS-C335568
Rabbit Polyclonal (IgG) to Human STXBP1 / MUNC18-1
Mouse, Rat, Human
IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded rat spleen tissue.
Immunohistochemistry of paraffin-embedded human esophageal cancer tissue.
Immunohistochemistry of paraffin-embedded rat spleen tissue.
Immunohistochemistry of paraffin-embedded human esophageal cancer tissue.

STXBP1 / MUNC18-1 Antibody LS-C402060
Rabbit Polyclonal (IgG) to Human STXBP1 / MUNC18-1
Mouse, Rat, Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human brain using STXBP1 Polyclonal Antibody at dilution of 1:25.
Immunohistochemistry of Human brain using STXBP1 Polyclonal Antibody at dilution of 1:25.

STXBP1 / MUNC18-1 Antibody LS-C341617
Rabbit Polyclonal to Human STXBP1 / MUNC18-1
Mouse, Rat, Human
IHC WB
Unconjugated
100µl 1mg/ml  $385.00

STXBP1 / MUNC18-1 Antibody (clone 1B9) LS-C348219
Mouse Monoclonal [clone 1B9] (IgG2b,k) to Human STXBP1 / MUNC18-1
Human
ELISA WB
Unconjugated
200µg  $365.00

STXBP1 / MUNC18-1 Antibody (250-330 aa) LS-C380904
Rabbit Polyclonal (IgG) to Human STXBP1 / MUNC18-1
Mouse, Rat, Human, Monkey
ELISA WB
Unconjugated
100µl 1mg/ml  $265.00

STXBP1 / MUNC18-1 Antibody (aa80-226) LS-C125908
Goat Polyclonal (IgG) to Human STXBP1 / MUNC18-1
Mouse, Rat, Human
ELISA WB
Unconjugated
100µg  $755.00

STXBP1 / MUNC18-1 Antibody (clone 1B9, HRP) LS-C347837
Mouse Monoclonal [clone 1B9] (IgG2b,k) to Human STXBP1 / MUNC18-1
Human
ELISA WB
HRP Conjugated
100µg  $355.00

STXBP1 / MUNC18-1 Antibody (clone 1B9, Biotin) LS-C347836
Mouse Monoclonal [clone 1B9] (IgG2b,k) to Human STXBP1 / MUNC18-1
Human
ELISA WB
Biotin Conjugated
100µg  $305.00

STXBP1 / MUNC18-1 Antibody (phospho-Ser313) LS-C199288
Rabbit Polyclonal (IgG) to Human STXBP1 / MUNC18-1
Mouse, Rat, Human
Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Western blot analysis of lysates from COS7 cells treated with PMA 125ng/ml 30', using MUNC-18a (Phospho-Ser313) Antibody. The lane on the right is blocked with the phospho peptide.
Western blot analysis of lysates from COS7 cells treated with PMA 125ng/ml 30', using MUNC-18a (Phospho-Ser313) Antibody. The lane on the right is blocked with the phospho peptide.

STXBP1 / MUNC18-1 Antibody LS-C489323
Rabbit Polyclonal to Human STXBP1 / MUNC18-1
Human
ELISA
Unconjugated
100µl  $255.00; 200µl  $305.00; 400µl  $355.00

STXBP1 / MUNC18-1 Antibody (aa504-553) LS-C102845
Rabbit Polyclonal (IgG) to Human STXBP1 / MUNC18-1
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
WB
Unconjugated
50µg  $365.00

STXBP1 / MUNC18-1 Antibody (aa1-603) LS-C132345
Rabbit Polyclonal to Human STXBP1 / MUNC18-1
Mouse, Human
WB
Unconjugated
100µg  $605.00
Showing 1-25 of 39 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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