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Anti-SPHK2 Antibody (N-Terminus) IHC-plus™ LS-B1101

Note: This antibody replaces LS-C26857

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $450
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SPHK2 Antibodies

Anti-SPHK2 Antibody (N-Terminus) IHC-plus™ LS-B1101
Rabbit Polyclonal to Human SPHK2
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-SPHK2 Antibody (aa590-620) LS-C100772
Rabbit Polyclonal to Human SPHK2
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-SPHK2 Antibody LS-C147009
Rabbit Polyclonal to Rat SPHK2
Rat, Human, Mouse
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human SPHK2
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Human SPHK2
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified

Applications

  • IHC - Paraffin (1 - 5 µg/ml)
  • Western blot
  • ELISA

Specificity and Use

SPHK2 antibody was raised against synthetic peptide from human SPHK2.
N-Terminus
Peptide from the N-terminus of human SPHK2 (long form)
Immunohistochemistry: LS-B1101 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1101 was determined to be 1-5 ug/ml.

Packaging

PBS, 0.08% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About SPHK2

Q9NRA0 NM_020126 NP_064511.2

SPHK2 Antibody, SK-2 Antibody, Sk2 Antibody, Sphingosine kinase type 2 Antibody, SPK-2 Antibody, Sphingosine kinase 2 Antibody, SPHK2L Antibody, SK 2 Antibody, SPK 2 Antibody

Unlike the proliferative action of SPHK1, SPHK2 has been shown to possess anti-proliferative or pro-apoptotic action. SphK2 suppresses growth and enhances apoptosis, independent of activation of S1P receptors. Sequence analysis revealed that SphK2 contains a 9 amino acid motif similar to that present in Bcl2-homology domain 3 (BH3)- only proteins, a pro-apoptotic subgroup of the Bcl-2 family.

Immunohistochemistry

Immunohistochemistry
Anti-SPHK2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1101 concentration 5 ug/ml.
 

Requested From: United States
Date Requested: 12/3/2016

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