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Anti-SOCS3 Antibody (clone 11C5) LS-C172981

Ordering

Wt. Vol. Conc. Price
- 100 µl 0.99 mg/ml $325
Inquire for larger quantities

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206-374-1102
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Most Popular SOCS3 Antibodies

Anti-SOCS3 Antibody (clone 11C5) LS-C172981
Mouse Monoclonal [clone 11C5] (IgG1) to Human SOCS3
Human
Immunofluorescence, Western blot, Flow Cytometry
Unconjugated
Immunofluorescence Image
Anti-SOCS3 Antibody (aa1-225, Biotin) LS-C297684
Rabbit Polyclonal (IgG) to Mouse SOCS3
Mouse
Western blot, ELISA
Biotin Conjugated
Western blot Image
Anti-SOCS3 Antibody (Internal) LS-C353123
Rabbit Polyclonal to Human SOCS3
Human, Mouse, Rat, Bovine, Dog, Pig, Sheep, Chicken
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 11C5] (IgG1) to Human SOCS3
Human
Immunofluorescence, Western blot, Flow Cytometry
Unconjugated

Details

Human SOCS3
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [11C5]
Unconjugated
Protein A/G purified
Unmodified

Applications

  • Immunofluorescence (1:100)
  • Western blot (1:2000)
  • Flow Cytometry (1:100)

Specificity and Use

SOCS3 antibody was raised against full length human recombinant protein of human SOCS3 (NP_003946) produced in HEK293T cell.
Human SOCS3

Packaging

PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About SOCS3

O14543 NM_003955 NP_003946.3

SOCS3 Antibody, Cish3 Antibody, Cytokine-induced SH2 protein 3 Antibody, CIS-3 Antibody, CIS3 Antibody, SSI-3 Antibody, STAT-induced STAT inhibitor 3 Antibody, SSI3 Antibody, ATOD4 Antibody, SOCS-3 Antibody

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors. Binding to JAK2 inhibits its kinase activity. Suppresses fetal liver erythropoiesis.

Immunofluorescence

Immunofluorescence
Anti-SOCS3 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SOCS3.

Western blot

Western blot
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SOCS3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SOCS3.

Flow Cytometry

Flow Cytometry
Flow cytometry of Jurkat cells, using anti-SOCS3 antibody (Red), compared to a nonspecific negative control antibody (Blue).

Flow Cytometry

Flow Cytometry
Flow cytometry of HeLa cells, using anti-SOCS3 antibody (Red), compared to a nonspecific negative control antibody (Blue).

Requested From: United States
Date Requested: 12/4/2016

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