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Anti-SOCS3 Antibody (aa213-225) LS-C55482

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml Unavailable

Most Popular SOCS3 Antibodies

Anti-SOCS3 Antibody (aa213-225) LS-C55482
Goat Polyclonal to Human SOCS3
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Pig, Rabbit
Western blot
Unconjugated
Western blot Image
Anti-SOCS3 Antibody (clone SO1) IHC-plus™ LS-B3317
Mouse Monoclonal [clone SO1] (IgG2b) to Human SOCS3
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-SOCS3 Antibody (clone 11C5) LS-C172981
Mouse Monoclonal [clone 11C5] (IgG1) to Human SOCS3
Human
Immunofluorescence, Western blot, Flow Cytometry
Unconjugated
Immunofluorescence Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human SOCS3
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Pig, Rabbit
Western blot
Unconjugated

Details

Human SOCS3
Goat
Human, Monkey, Mouse, Rat, Bat, Bovine, Hamster, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Dog, Chicken (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot (4 - 6 µg/ml)
IHC - Paraffin

Specificity and Use

SOCS3 antibody was raised against synthetic peptide C-PIREFLDQYDAPL from the C-terminus of human SOCS3 (NP_003946.3). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bat, Bovine, Horse, Rabbit, Pig, Opossum (100%); Dog, Chicken, Platypus (92%); Lizard (85%).
LS-E25197 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C55482. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa213-225
Human SOCS3.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About SOCS3

O14543 NM_003955 NP_003946.3

SOCS3 Antibody, Cish3 Antibody, Cytokine-induced SH2 protein 3 Antibody, CIS-3 Antibody, CIS3 Antibody, SSI-3 Antibody, STAT-induced STAT inhibitor 3 Antibody, SSI3 Antibody, ATOD4 Antibody, SOCS-3 Antibody

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors. Binding to JAK2 inhibits its kinase activity. Suppresses fetal liver erythropoiesis.

Western blot

Western blot
Antibody staining (5 ug/ml) of MOLT-4 lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.
 

Requested From: 
Date Requested: 3/30/2017

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