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Anti-SMAD3 Antibody (aa206-220) LS-C152733

Note: This antibody replaces LS-C10219

Ordering

Wt. Vol. Conc. Price
400 µg - - $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SMAD3 Antibodies

Anti-SMAD3 Antibody (phospho-Ser423/Ser425) IHC-plus™ LS-B64
Rabbit Polyclonal to Human SMAD3
Human, Mouse, Rat, Bovine, Pig, Chicken, Xenopus, Zebrafish
IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Unconjugated
Immunohistochemistry Image
Anti-SMAD3 Antibody (C-Terminus) LS-C46894
Rabbit Polyclonal to Human SMAD3
Human
Western blot, ELISA
Unconjugated
Anti-SMAD3 Antibody (aa100-150) IHC-plus™ LS-B2064
Rabbit Polyclonal to Human SMAD3
Human, Monkey, Mouse, Rat, Bovine, Dog, Pig, Macaque
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human SMAD3
Human, Monkey, Mouse, Rat, Dog, Hamster, Horse, Pig, Chicken
Western blot
Unconjugated

Details

Human SMAD3
Rabbit
Human, Monkey, Mouse, Rat, Dog, Hamster, Horse, Pig, Chicken (tested or 100% immunogen sequence identity)
Bovine, Guinea pig, Zebrafish (at least 90% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Protein A purified
Unmodified

Applications

Western blot

Specificity and Use

SMAD3 antibody was raised against peptide [C-NLSPNPMSPAHNNLD-amide] corresponding to amino acids 206-220 of human Smad3 Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Horse, Pig, Opossum, Zebra finch, Chicken, Platypus, Lizard (100%); Bovine, Guinea pig, Zebrafish (93%); Xenopus, Pufferfish (80%).
aa206-220
Smad3

Packaging

0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol
Store at -20°C.
For research use only.

About SMAD3

P84022 NM_005902 NP_005893.1

SMAD3 Antibody, HSPC193 Antibody, HMAD-3 Antibody, HsT17436 Antibody, LDS1C Antibody, LDS3 Antibody, Mad homolog JV15-2 Antibody, MAD3 Antibody, MADH3 Antibody, Mothers against DPP homolog 3 Antibody, JV15-2 Antibody, SMA- and MAD-related protein 3 Antibody, SMAD family member 3 Antibody, MAD homolog 3 Antibody, HSMAD3 Antibody, Mad protein homolog Antibody, SMAD 3 Antibody

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription.

Western blot

Western blot
WB: HepG2 cell lysate was probed with anti-Smad3 (2g/ml) preincubated with (lane 1) or without (lane 2) immunogenic peptide.
 

Requested From: United States
Date Requested: 12/3/2016

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