Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal (IgG1) to Human SLPI / Antileukoproteinase
IHC - Paraffin, IHC - Frozen, Western blot
Human SLPI / Antileukoproteinase
Human (tested or 100% immunogen sequence identity)
IHC - Paraffin (1:10)
IHC - Frozen (1:10)
Western blot (1:10)
Specificity and Use
Reacts specifically with secretory leukocyte proteinase inhibitor (SLPI; also known as antileukoprotease or ALP).
Can be used for Immunohistology on frozen and paraffin sections. Furthermore the antibody is useful for Western Blot and immunoassays. Immunohistology: 1:10. Western Blot: 1:10. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, 0.02% sodium azide, 0.1% BSA.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
SLPI is a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes. This antimicrobial protein has antibacterial, antifungal and antiviral activity.