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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SLC5A5 / NIS Antibody (aa37‑54) LS‑C16858 Best Seller
Antibody
NIS antibody LS-C16858 is an unconjugated mouse monoclonal antibody to human NIS (SLC5A5). Validated for IHC and WB.
Catalog
Size
Price
LS-C16858-100
100 µg (1 mg/ml)
Unavailable

Popular SLC5A5 / NIS Products

Antibody
Species: Rat
Applications: IHC, Immunofluorescence, Western blot, ELISA
Formalin-fixed, paraffin-embedded human thyroid gland stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of follicular epithelium.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Formalin-fixed, paraffin-embedded human thyroid gland stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of follicular epithelium.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Western blot analysis of Sodium Iodide Symporter, Clone FP5, tested on human retina lysate, using a 1:1000 dilution of SLC5A5 / NIS antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat
Applications: IHC, Immunofluorescence, Western blot, ELISA

Product Description

NIS antibody LS-C16858 is an unconjugated mouse monoclonal antibody to human NIS (SLC5A5). Validated for IHC and WB.
About SLC5A5 / NIS
SLC5A5 / NIS is a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1. Q92911 NM_000453 NP_000444.1

SLC5A5 Antibody, Sodium-iodide symporter Antibody, Na(+)/I(-) cotransporter Antibody, NIS Antibody, Sodium/iodide cotransporter Antibody, Na(+)/I(-) symporter Antibody, Na+/I- symporter Antibody, TDH1 Antibody


Specifications

Target
Human SLC5A5 / NIS
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Western blot
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
SLC5A5 / NIS antibody was raised against synthetic peptide corresponding to aa37-54 of human NIS.
Epitope
aa37-54
Specificity
Recognizes human Sodium/Iodide Symporter (NIS). Recognizes a major band at ~97kD and minor bands at 15kD, 30kD, 68kD and 160kD.
Usage
Suitable for use in Western Blot and Immunohistochemistry. Immunohistochemistry: Use on paraffin embedded tissue sections which have been subjected to antigen retrieval with 10 mM citrate buffer steam for 30 minutes.
Presentation
PBS, 0.1% sodium azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/17/2018

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