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Anti-SLC12A5 / KCC2 Antibody (N-Terminus) LS-C24944

Catalog Size Price
LS-C24944-100 100 µg Unavailable

Related Products

44 SLC12A5 / KCC2 Antibodies

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Anti-SLC12A5 / KCC2 Antibody (N-Terminus) LS-C24943
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Anti-SLC12A5 / KCC2 Antibody (aa971-1020) LS-C110846
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Anti-SLC12A5 / KCC2 Antibody (N-Terminus) LS-C135150
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Anti-SLC12A5 / KCC2 Antibody (clone S1-12) LS-C150467
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Anti-SLC12A5 / KCC2 Antibody (aa12-41) LS-C325140
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100% Guaranteed
Rabbit Polyclonal (IgG) to Rat SLC12A5 / KCC2
Rat, Dog
ICC, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Rat SLC12A5 / KCC2
Rabbit
Rat, Dog (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Protein A purified
Unmodified

Applications

  • ICC (1:200)
  • Western blot (1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

SLC12A5 / KCC2 antibody was raised against n-terminal His-tag fusion protein corresponding to residues 932-1043 of rat K+/Cl- Cotransporter (KCC2).
N-Terminus
Recognizes rat K+/Cl- Cotransporter (KCC2), Mr ~140kD. An unknown band >200kD was also detected. Species cross-reactivity: Canine. Wide range of species cross-reactivity expected due to sequence homology.
Suitable for use in Western Blot and Immunocytochemistry. Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Immunocytochemistry: 1:200 detected KCC2 in MDCK cells as reported by an independent laboratory.

Packaging

0.07 M Tris-glycine, pH 7.4, 0.105 M sodium chloride, 0.035% sodium azide, 30% glycerol.
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About SLC12A5 / KCC2

Q9H2X9 NM_020708 NP_065759.1

SLC12A5 Antibody, Erythroid K-Cl cotransporter 2 Antibody, HKCC2 Antibody, K-Cl cotransporter 2 Antibody, KCC2 Antibody, KIAA1176 Antibody, Neuronal K-Cl cotransporter Antibody

K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons.

Requested From: 
Date Requested: 8/16/2017

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