Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human SIRT3 / Sirtuin 3
IHC - Paraffin, Western blot, ELISA
Goat Polyclonal to Human SIRT3 / Sirtuin 3
Western blot, ELISA
Human SIRT3 / Sirtuin 3
Human (tested or 100% immunogen sequence identity)
Western blot (1:128000) & (0.1 - 0.3 µg/ml)
IHC - Paraffin
Specificity and Use
SIRT3 / Sirtuin 3 antibody was raised against synthetic peptide C-QRETGKLDGPDK from the C-terminus of human SIRT3 (NP_036371.1, NP_001017524.1). Percent identity by BLAST analysis: Human, Gorilla (100%).
LS-E25972 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C55469. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human SIRT3. This antibody is expected to recognize both reported isoforms (NP_036371.1 and NP_001017524.1).
SIRT3 Antibody, HSIRT3 Antibody, Sir2-like 3 Antibody, SIR2-like protein 3 Antibody, SIR2L3 Antibody, Sirtuin 3 Antibody, Sirtuin type 3 Antibody
SIRT3 / Sirtuin 3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA.