Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
SH3GL1 Antibody, CNSA1 Antibody, Endophilin-A2 Antibody, Endophilin-2 Antibody, Extra 11-19 leukemia fusion Antibody, SH3-domain GRB2-like 1 Antibody, SH3 domain protein 2B Antibody, EEN Antibody, EEN fusion partner of MLL Antibody, SH3D2B Antibody, SH3P8 Antibody
SH3GL1 / EEN is a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17.
IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-SH3GL1 mouse monoclonal antibody.
Anti-SH3GL1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SH3GL1.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SH3GL1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SH3GL1.
Western blot of extracts (35 ug) from 9 different cell lines by using anti-SH3GL1 monoclonal antibody.
Flow cytometry of Jurkat cells, using anti-SH3GL1 antibody, (Red), compared to a nonspecific negative control antibody, (Blue).
Flow cytometry of HeLa cells, using anti-SH3GL1 antibody, (Red), compared to a nonspecific negative control antibody, (Blue).