Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse (tested or 100% immunogen sequence identity)
IHC (2 - 5 µg/ml), Western blot (0.1 - 0.2 µg/ml)
Specificity and Use
SFRP-3 / FRZB antibody was raised against nS0-derived rmsFRP-3.
Recognizes mouse sFRP-3.
Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 0.1-0.2 ug/ml; The detection limit is ~5 ng/lane under non-reducing and reducing conditions. In this format, this antibody shows ~60% cross-reactivity with rhsFRP-3. Immunohistochemistry: 2-5 ug/ml; Will detect sFRP-3 in cells and tissues.
Lyophilized powder from PBS, BSA.
50 µl Reconstitute with 1ml sterile 40-50% glycerol, ddH2O.
+4°C or -20°C, Avoid repeated freezing and thawing.
FRZB Antibody, FRZB-1 Antibody, FIZ Antibody, FRE Antibody, FRITZ Antibody, Fritz and frizzled Antibody, Frizzled homolog-related Antibody, FRP-3 Antibody, FRZB-PEN Antibody, HFIZ Antibody, FRP Antibody, FZRB Antibody, SFRP-3 Antibody, SRFP3 Antibody, OS1 Antibody, Frezzled Antibody, Frizzled related protein 3 Antibody, Frizzled-related protein Antibody, Frizzled-related protein 1 Antibody, FRZB1 Antibody, SFRP3 Antibody
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.