Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 1.2B6] (IgG1) to Human SELE / CD62E / E-selectin
IHC, Flow Cytometry, ELISA
Human SELE / CD62E / E-selectin
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [1.2B6]
Protein G purified
ELISA (2 - 5 µg/ml)
Specificity and Use
SELE / CD62E / E-selectin antibody was raised against tNF-activated human umbilical endothelial cells.
Recognizes CD62Epositive cells. CD62E is the type 1 transmembrane glycoprotein also known as E-selectin or endothelial- leukocyte adhesion molecule-1 (ELAM1). It is expressed on cytokine stimulated endothelial cells.
PBS, pH 7.4, 0.1% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
SELE / CD62E / E-selectin is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules.