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Anti-RPS6KB1 / P70S6K / S6K Antibody (aa490-502) IHC-plus™ LS-B4439

Note: This antibody replaces LS-C34650

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular RPS6KB1 / P70S6K / S6K Antibodies

Anti-RPS6KB1 / P70S6K / S6K Antibody (phospho-Thr398) LS-C25949
Rabbit Polyclonal to Drosophila RPS6KB1 / P70S6K / S6K
Drosophila, Human
Western blot
Unconjugated
Anti-RPS6KB1 / P70S6K / S6K Antibody (phospho-Thr389) LS-C146919
Rabbit Polyclonal to Human RPS6KB1 / P70S6K / S6K
Human, Mouse, Rat
Western blot
Unconjugated
Anti-RPS6KB1 / P70S6K / S6K Antibody (clone 5G9) LS-C169467
Mouse Monoclonal [clone 5G9] (IgG1) to Human RPS6KB1 / P70S6K / S6K
Human
IHC - Paraffin, Western blot, Flow Cytometry, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human RPS6KB1 / P70S6K / S6K
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Goat, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus
IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Human RPS6KB1 / P70S6K / S6K
Goat
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Goat, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus (tested or 100% immunogen sequence identity)
Zebrafish (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (3.75 µg/ml)
  • Western blot (0.2 - 1 µg/ml)
  • ELISA (1:128000)

Specificity and Use

RPS6KB1 / P70S6K / S6K antibody was raised against synthetic peptide C-MISKRPEHLRMNL from the C-terminus of human RPS6KB1 / S6K (NP_003152.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Goat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Xenopus (100%); Stickleback, Zebrafish (92%).
LS-E25426 - Lyophilized - 100 µg - $145.00
aa490-502
Human RPS6KB1 / S6K.
Peptide ELISA: antibody detection limit dilution 1:128000. Western blot: Approx 65-70 kDa band observed in Human Skeletal Muscle and Placenta lysates (predicted MW of 60 kDa according to NP_003152.1). Recommended for use at 0.2-1 ug/ml.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About RPS6KB1 / P70S6K / S6K

P23443 NM_003161 NP_003152.1

RPS6KB1 Antibody, 70 kDa S6 kinase Antibody, p70 S6KA Antibody, p70-alpha Antibody, p70-S6K Antibody, p70 S6 kinase alpha Antibody, p70s6 kinase Antibody, S6K-beta-1 Antibody, STK14A Antibody, p70 ribosomal S6 kinase Antibody, p70 S6 kinase, alpha 1 Antibody, p70 S6 kinase, alpha 2 Antibody, p70 S6K-alpha Antibody, p70-S6K 1 Antibody, p70S6K Antibody, p70S6K1 Antibody, PS6K Antibody, Ribosomal protein S6 kinase I Antibody, S6K Antibody, S6K1 Antibody, p70 ribosomal S6 kinase alpha Antibody, p70(S6K)-alpha Antibody

Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex.

Immunohistochemistry

Immunohistochemistry
Anti-RPS6KB1 / S6K antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4439 concentration 3.75 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-RPS6KB1 / S6K antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4439 concentration 3.75 ug/ml.

Western blot

Western blot
RPS6KB1 antibody staining (0.2 ug/ml) of Human Muscle lysate (RIPA buffer, 35g total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.
 

Requested From: United States
Date Requested: 12/10/2016

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