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RBP4 belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.
Gene Name: | retinol binding protein 4, plasma |
Synonyms: | RBP4, PRBP, Plasma retinol-binding protein, RBP, Retinol-binding protein 4 |
Target Sequences: | NM_006744 NP_006735.2 P02753 |
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