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Human RASSF1 / RASSF1A | |
Rabbit | |
Human, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Sheep, Zebrafish (tested or 100% immunogen sequence identity) | |
Monkey, Guinea pig, Rabbit (at least 90% immunogen sequence identity) | |
Polyclonal | |
Unconjugated. Also available conjugated with Biotin, FITC, HRP. | |
Immunoaffinity purified | |
Unmodified |
Synthetic peptide located between aa201-250 of human RASSF1 (Q9NS23, NP_733831). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Mouse, Rat, Sheep, Hamster, Elephant, Dog, Bovine, Bat, Horse, Pig (100%); Marmoset, Rabbit, Guinea pig (92%); Platypus, Lizard, Xenopus (85%); Panda, Opossum, Turkey, Zebra finch, Chicken, Stickleback (84%). | ||
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aa201-250 | ||
Human RASSF1 / RASSF1A | ||
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody. |
Lyophilized from PBS with 2% sucrose | |
Distilled water | |
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles. | |
For research use only. |
RASSF1 Antibody, 123F2 Antibody, RASSF1A Antibody, RDA32 Antibody, Tumor suppressor protein RDA32 Antibody, NORE2A Antibody, WUGSC:H_LUCA12.5 Antibody, REH3P21 Antibody
Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Isoform A interacts with CDC20, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression.
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