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Anti-QIP1 / KPNA4 Antibody (aa459-521) LS-C185791

Catalog Size Price
LS-C185791-100 100 µl (0.73 mg/ml) Unavailable

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26 QIP1 / KPNA4 Antibodies

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Anti-QIP1 / KPNA4 Antibody (clone 2500D3a) LS-C342520
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Anti-QIP1 / KPNA4 Antibody (aa471-521) IHC-plus™ LS-B12404
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Anti-QIP1 / KPNA4 Antibody (aa38-87, Biotin) LS-C458948
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Anti-QIP1 / KPNA4 Antibody LS-C499200
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100% Guaranteed
Rabbit Polyclonal (IgG) to Human QIP1 / KPNA4
Human, Bovine
IHC - Paraffin, ICC, Western blot
Unconjugated

Details

Human QIP1 / KPNA4
Rabbit
Human, Bovine (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (1:100 - 1:1000)
  • ICC (1:100 - 1:1000)
  • Western blot (1:500 - 1:3000)

Specificity and Use

QIP1 / KPNA4 antibody was raised against synthetic peptide corresponding to a region within amino acids 459 and 521 of KPNA4 (SwissProt O00629). Percent identity by BLAST analysis: Human, Bovine (100%).
aa459-521
Human QIP1 / KPNA4
IHC-paraffin: Suggested antigen retrieval using heat mediated 10 mM Citrate buffer (pH 6.0) or Tris-EDTA buffer (pH 8.0).

Packaging

PBS, pH 7.0, 10% glycerol, 0.01% Thimerosal
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
For research use only.

About QIP1 / KPNA4

NM_002268 NP_002259.1

KPNA4 Antibody, Importin subunit alpha-4 Antibody, Importin alpha Q1 Antibody, Karyopherin subunit alpha-4 Antibody, SRP3 Antibody, IPOA3 Antibody, QIP1 Antibody

Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.

Immunohistochemistry

Immunohistochemistry
IHC of paraffin-embedded H1299 xenograft using KPNA4 antibody at 1:500 dilution.

Immunocytochemistry

Immunocytochemistry
Immunofluorescence of paraformaldehyde-fixed HeLa using QIP1 antibody at 1:200 dilution.

Western blot

Western blot
Sample (30 ug of whole cell lysate). A:293T, B: HepG2, C: Molt-4 . 7.5% SDS PAGE. QIP1 / KPNA4 antibody diluted at 1:1500.

Requested From: 
Date Requested: 12/14/2017

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