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QIP1 / KPNA4

karyopherin alpha 4 (importin alpha 3)

Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.

Gene Name: karyopherin alpha 4 (importin alpha 3)
Synonyms: KPNA4, Importin subunit alpha-4, Importin alpha Q1, Karyopherin subunit alpha-4, SRP3, IPOA3, QIP1
Target Sequences: NM_002268 NP_002259.1

☰ Filters
Antibodies (26)
Proteins (4)
Over-Expression Lysate (2)
Primary (26)
Recombinant (2)
QIP1 / KPNA4 (30)
Human (26)
Mouse (19)
Rat (9)
Bat (4)
Bovine (5)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (3)
Hamster (4)
Horse (4)
Monkey (4)
Orangutan (3)
Rabbit (4)
IHC (11)
IHC-P (5)
WB (22)
ELISA (12)
ICC (2)
IF (8)
IP (1)
Peptide-ELISA (2)
rabbit (25)
goat (1)
Product Group
IHCPlus (3)
IgG (22)
polyclonal pc (26)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (15)
aa1-30 (7)
aa38-87 (4)
aa471-521 (2)
aa459-521 (1)
aa509-521 (1)
No (30)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
QIP1 / KPNA4 Antibody - Anti-KPNA4 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
QIP1 / KPNA4 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal (aa471-521) Antibody
Mouse, Human
IF, IHC, IHC-P
Unconjugated
50 µl/$460
QIP1 / KPNA4 Antibody - Immunohistochemistry of paraffin-embedded human testis tissue using KPNA4 Antibody at dilution of 1:100
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
QIP1 / KPNA4 Antibody - Anti-KPNA4 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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QIP1 / KPNA4 Goat anti-Human Polyclonal (aa509-521) Antibody
Rabbit, Dog, Bovine, Hamster, Horse, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
QIP1 / KPNA4 Antibody - IHC of paraffin-embedded H1299 xenograft using KPNA4 antibody at 1:500 dilution.
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal (aa459-521) Antibody
Bovine, Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
QIP1 / KPNA4 Antibody - Immunohistochemistry of paraffin-embedded rat brain tissue.
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
QIP1 / KPNA4 Antibody - 1:100 staining mouse testis tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
QIP1 / KPNA4 Protein - 12.5% SDS-PAGE of human KPNA4 stained with Coomassie Blue
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Wheat Germ Extract
GST
84.3 kDa
10 µg/$479; 25 µg/$670
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
QIP1 / KPNA4 Antibody - Detection of Human KPNA4 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-KPNA4 used at a dilution of 1:200 (1 Detection: DAB.
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal (aa471-521) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
QIP1 / KPNA4 Antibody - Immunohistochemical analysis of Karyopherin alpha-4 staining in human esophageal cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
QIP1 / KPNA4 Antibody - Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal (aa38-87) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
QIP1 / KPNA4 Antibody - Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal (aa38-87) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
QIP1 / KPNA4 Antibody - The anti-Importin alpha-3 antibody is used in Western blot to detect Importin alpha-3 in HeLa (left), mouse brain (middle), and HepG2 (right)cell line/tissue lysates.
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QIP1 / KPNA4 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
Viewing 1-25 of 30 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).