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Anti-PTPN22 / PEP Antibody (aa663-691) LS-C162305

Catalog Size Price
LS-C162305-400 400 µl Unavailable

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100% Guaranteed
Rabbit Polyclonal to Human PTPN22 / PEP
Western blot


Human PTPN22 / PEP
Human (tested or 100% immunogen sequence identity)
Protein A purified


Western blot (1:1000)

Specificity and Use

LS-E4413 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C162305. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
This PTPN22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 663-691 amino acids from the C-terminal region of human PTPN22.


PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About PTPN22 / PEP

Q9Y2R2 NM_015967 NP_057051.3

PTPN22 Antibody, 70zpep Antibody, Lymphoid phosphatase Antibody, LYP Antibody, PEST-domain phosphatase Antibody, LYP2 Antibody, LYP1 Antibody, PEP Antibody, PTPN8 Antibody

Acts as negative regulator of T-cell receptor (TCR) signaling by direct dephosphorylation of the Src family kinases LCK and FYN, ITAMs of the TCRz/CD3 complex, as well as ZAP70, VAV, VCP and other key signaling molecules. Associates with and probably dephosphorylates CBL. Dephosphorylates LCK at its activating 'Tyr-394' residue. Dephosphorylates ZAP70 at its activating 'Tyr-493' residue. Dephosphorylates the immune system activator SKAP2.

Western blot

Western blot
PTPN22 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The PTPN22 antibody detected the PTPN22 protein (arrow).

Requested From: 
Date Requested: 1/19/2018

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