Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Western blot (1:100 - 1:500)
Specificity and Use
PRMT5 antibody was raised against synthetic peptide from C-terminus of human PRMT5.
Reacts with PRMT5 (Protein Arginine N-Methytransferase 5). Species cross-reactivity: Human.
Suitable for use in Western Blot, ELISA. Western Blot: 1:100-1:500. Reacts with a band of approximately 70kD on whole HL60 cell lysate. Additional bands may be present depending on sample used. ELISA (direct): 1:1000.
PBS, pH 7.2, 0.1% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
PRMT5 Antibody, 72 kDa ICln-binding protein Antibody, HRMT1L5 Antibody, JBP1 Antibody, Jak-binding protein 1 Antibody, IBP72 Antibody, SKB1Hs Antibody, SKB1 Antibody, SKB1 homolog Antibody, Skb1 (S. pombe) homolog Antibody, SKB1 homolog (S. pombe) Antibody
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H.